Project description
Solution from silk fibroin for peripheral nerve reparation
Peripheral nerve injuries cause significant disability by impairing muscle movement and normal sensations, leading to a substantial socio-economic burden. Unfortunately, current treatments often fail to restore full motor and sensory functions, resulting in the loss of sensation, function, and chronic pain. The EIC-funded KLISBio project has developed SILKBridge, a new, cost-effective nerve guide made from silk fibroin that repairs peripheral nerves safely and effectively. Clinically tested in a first-in-human (FIH) study, SILKBridge supports and protects regenerating nerves from compressive forces while enhancing nerve healing without causing immune rejection or fibrosis. This innovation reduces costs associated with rehabilitation and prolonged surgeries.
Objective
Peripheral nerve injury is a major source of disability, impairing muscle movement or normal sensations: 4Mn people annually experience traumatic nerve damage. Current solutions do not always achieve full motor and sensory recovery, leading to loss of sensation/function and pain, with a significant impact to patients lives. With 50% unsuccessful nerve repair procedures, patients require prolonged rehabilitation, and 30% of them experience permanent disability, producing a high socio-economic burden. KLISBio has developed SILKBridge, a novel cost-effective nerve guide made of silk fibroin for safe and efficient peripheral nerve repair. KLISBios solution, clinically tested with a first in human (FIH) study, supports and protects the regenerating nerve from compressive forces, restoring its function, and reducing pain without patient discomfort. SILKBridge enhances nerve healing without immune rejection nor fibrosis, reducing the costs of rehabilitation and prolonged surgeries.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine surgery
- medical and health sciences clinical medicine physiotherapy
You need to log in or register to use this function
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2023-ACCELERATOR-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
20091 BRESSO (MI)
Italy
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.