Objective
Rhythmic peripheral signals like respiratory, cardiac, and gastric activity not only serve our bodies’ strive for homeostasis, but actively modulate brain activity and behaviour. However, what are the functional mechanisms and signalling pathways by which these rhythms orchestrate brain function? An ever-growing number of studies show that body-brain interactions are of prime importance when we assign functional roles to brain activity. Yet, little is known about how body-brain coupling is governed by states of the body (e.g. breathing interventions) and the brain (e.g. emotional or excitability states). Critically, these gaps also extend to studies in disease, which currently limits our understanding of how embodied processing contributes to pathology. Generally, it is unclear how multimodal physiological rhythms interact not only with each other, but also with high-dimensional brain dynamics. I will address these challenges by combining state-of-the-art MEG neuroimaging, computational modelling, and comprehensive physiological recordings to develop a novel framework of body-brain dynamics in health and disease. I will probe body-brain coupling in consequence of short-term changes in body and brain states, i.e. induced by experimental manipulation (breathing interventions, cognitive-emotional tasks), longer-term changes like circadian rhythms, and pathological alterations of excitability states or respiratory mechanics. To widen the scope towards multimodal body-brain interactions, I will assess the link of respiratory and gastric rhythms with non-invasive olfactory bulb recordings during edible odour processing. This lays the groundwork for developing the first computational model describing whole-body-whole-brain interactions. Overall, this project will establish an explanatory model to describe function and dysfunction of multimodal body-brain coupling and redefine the way we conceptualise, investigate, and ultimately understand the interplay of body and brain.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pathology
- medical and health sciences basic medicine physiology homeostasis
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2024-STG
See all projects funded under this callHost institution
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
48149 Muenster
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.