Project description
Understanding brain plasticity in blind individuals
In blind individuals, the early visual cortex – typically responsible for processing visual information – responds to language, raising questions about brain plasticity and the specific language aspects represented in this area. The ERC-funded BLINDBRAIN project will investigate two hypotheses regarding language processing in the early visual cortex. The first proposes that linguistic effects stem from typical visuospatial computations, emphasising the concrete properties of language. The second suggests that responses are driven by abstract representations, enabling the processing of conceptual aspects of language. Using neuroimaging techniques, the project aims to test these hypotheses and deepen our understanding of how sensory experiences and genetics shape cognitive functions in the brain.
Objective
What makes the cognitive functions to always fall in the same brain niches, in people all around the world? This consistency might be driven by shared experience, characteristic of our species. Alternatively, it might be driven by genetic blueprints, predisposing certain brain areas to process specific types of information.
To tackle this puzzle, I want to understand the functional plasticity of the early visual cortex, genetically predisposed to process vision, in people born blind. We know that, in blind individuals, this brain region responds to language. While this discovery can be groundbreaking for our theories of brain plasticity, its theoretical implications are debated, particularly because we do not know what properties of linguistic stimuli are represented in the blind early visual cortex.
The project objective is to fill this gap in knowledge and disentangle two hypotheses for language processing in the early visual cortex of blind individuals. One hypothesis is that linguistic effects in this region are an extension of its typical visuospatial computations. That implies that this region represents linguistic stimuli through concrete, physical properties of language referents. An alternative possibility is that responses to language in the blind early visual cortex are driven by the development of truly abstract representation in this region. That implies that this region can represent more conceptual properties of language referents or even the linguistic properties of words and expressions themselves.
My project will use advanced neuroimaging approaches, such as “mind reading” from fMRI signals and inducing “virtual lesions” with TMS, to thoroughly test these two hypotheses. By doing so, it will evaluate two fundamentally different perspectives on functional plasticity in the human brain, and will significantly improve our understanding of how sensory experience and genetic blueprints shape the implementation of cognitive functions in this organ.
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Keywords
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2024-STG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
31-007 Krakow
Poland
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