Objective
Targeted radionuclide therapy (TRT) uses radiopharmaceuticals to selectively deliver radiation to cancerous cells at specific target organs. A precise quantification of the radiation dose delivered to lesions and organs at risk is crucial for improving patient treatment safety and reducing related side effects. Imaging systems play a key role in this task although, in many cases, with sub-optimal performance.
Alpha-emitting radionuclides are gaining prominence due to their exceptional cytotoxicity. For them, image-based dosimetry is an unmet need as currently used gamma cameras are not effective in the case of these high energy and low activity emitters.
The AIDER project aims at developing a specialized imaging tool based on Compton Camera (CC) technology to improve imaging in TRT and to enable image-based dosimetry in targeted alpha therapy. AIDER will optimize existing CC technology by pushing the limits in the system performance through the integration of cutting-edge detectors and electronics. Monte Carlo simulations will guide the system optimization and the development of advanced image reconstruction codes aimed at paving the way for quantitative imaging and thus extending the use of CCs to dosimetry applications. The system developed will be tested in hospitals at three levels to evaluate its performance: from simple tests with 3D printed phantoms to anthropomorphic phantoms specifically designed to reproduce the distribution of radionuclides in the body, and finally with patients undergoing TRT.
The consortium integrates most of the main European experts in CCs from different disciplines, including four academic groups, a research-intensive SME, two hospitals, and a patient association. They will collaborate with a focus on significantly improving image quality and sensitivity towards enabling per-treatment imaging as the most effective way to estimate the dose-effect relationship and thus to personalize radionuclide therapies for cancer patients.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors optical sensors
- natural sciences chemical sciences nuclear chemistry radiation chemistry
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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EURATOM2027 - Euratom Research and Training Programme (EURATOM)
MAIN PROGRAMME
See all projects funded under this programme -
EURATOM.1.1.4 - Nuclear science and ionizing radiation applications, radiation protection, emergency preparedness
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
EURATOM-IA - EURATOM Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EURATOM-2023-NRT-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.