Reducing Non-Human Primates in Non-Clinical Safety Assessment: The European Initiative on Minipig and Micropig Models

Project Information

NHPig

Grant agreement ID: 101165643

DOI

10.3030/101165643

EC signature date 12 November 2024

Start date 1 October 2024

End date 30 September 2029

Funded under

• Health

Total cost

€ 17 522 696,50

EU contribution

€ 8 499 555,50

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Corrigendum to “Considerations for use of humanized IgG1/4 Göttingen minipigs in safety assessment of antibody-based therapeutics” [Regul. Toxicol. Pharmacol., (161) (2025) 105855]

Author(s): Anna Engstrom, Tine Dahlbaek Hannibal, Jerome Egli, Beatrice Gauthier, Mikkel Lykke Krarup, Daniela Gallo, Andres Eskjær Jensen, Steven Van Cruchten, Steven Bulera, Miranda Cornet, Sabine Elisabeth Hammer, David Henry, Bjoern Jacobsen, John Kendrick, Lars Siim Madsen, Sofiene Mhedhbi, Steven Oag, Henrik Duelund Pedersen, Manuela Teti, Pramila Singh
Published in: Regulatory Toxicology and Pharmacology, Issue 162, 2025, ISSN 0273-2300
Publisher: Elsevier BV
DOI: 10.1016/J.YRTPH.2025.105908

Considerations for use of humanized IgG1/4 Göttingen minipigs in safety assessment of antibody-based therapeutics

Author(s): Anna Engstrom, Tine Dahlbaek Hannibal, Jerome Egli, Beatrice Gauthier, Mikkel Lykke Krarup, Daniela Gallo, Andres Eskjær Jensen, Steven Van Cruchten, Steven Bulera, Miranda Cornet, Sabine Elisabeth Hammer, David Henry, Bjoern Jacobsen, John Kendrick, Lars Siim Madsen, Sofiene Mhedhbi, Steven Oag, Henrik Duelund Pedersen, Manuela Teti, Pramila Singh
Published in: Regulatory Toxicology and Pharmacology, Issue 161, 2025, ISSN 0273-2300
Publisher: Elsevier BV
DOI: 10.1016/J.YRTPH.2025.105855

Reproduction, Fertility and Development

Author(s): Eckhard Wolf, Asghar Ali, Andreas Blutke, Michaela Blasi, Thomas Fröhlich, Arne Hinrichs, Hristiyan Hristov, Florian Jaudas, Elisabeth Kemter, Barbara Keßler, Nikolai Klymiuk, Mayuko Kurome, Simone Renner, Valeri Zakhartchenko
Published in: Reproduction, Fertility and Development, Issue RD25164 (Just accepted, no volume/issue yet), 2025, ISSN 1031-3613
Publisher: Commonwealth Scientific and Industrial Research Organization Publishing
DOI: 10.1071/RD25164

Protocol for in vivo assessment of glucose control and insulin secretion and sensitivity in the pig

Author(s): Yasmin Eckstein, Barbara Kessler, Arne Hinrichs, Istvan Novak, Anne von Thaden, Timo Lorenzen, Birgit Rathkolb, Armin Scholz, Andreas Blutke, Sietse-Jan Koopmans, Martin Hrabĕ de Angelis, Berit Østergaard Christoffersen, Eckhard Wolf, Simone Renner
Published in: STAR Protocols, Issue 6, 2025, ISSN 2666-1667
Publisher: Elsevier BV
DOI: 10.1016/J.XPRO.2025.103774