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Innovative approaches to implantation research in health and disease

Objective

Implantation of the embryo in a receptive uterus is critical for mammalian reproduction, yet remains poorly understood. This challenge is particularly significant in human health, as up to two-thirds of human pregnancies are lost due implantation failure. In the agricultural sector, particularly in sustainable milk and meat production, understanding and improving embryo implantation is equally crucial. High peri-implantation mortality rates in livestock lead to lower efficiency, profitability, and environmental sustainability. Much remains unknown about the molecular pathways and regulatory mechanisms of embryo-endometrial interactions in humans and livestock species. For ethical and practical reasons, implantation cannot be adequately studied in vivo in human, and it remains challenging in most animal models.
IMPLANTEU is an international community of researchers whose objectives are:
1) To develop a molecular blueprint of human implantation in health and disease;
2) To improve implantation fitness for food production mammals and
3) To develop an advanced toolkit for implantation research.
IMPLANTEU provides multi-species, multi-sector and multi-model molecular and system implantation research, integrating complementary expertise in reproductive and stem cells biology, medicine, physiology, ethics and law, and cutting-edge technologies such as stem cell-based embryo models, organoids, machine learning, and organ-on-chip.
IMPLANTEU will train 13 doctoral candidates through research, innovation, secondments in academic and industrial environments, horizontal and focused courses, and interactions with stakeholders. The findings generated through IMPLANTEU will contribute to the profound understanding of the embryonic and endometrial contribution to reproductive success, innovations in infertility treatment, animal production efficiency and sustainability, tissue bioengineering, pathogen-host interaction, reproductive toxicology, and stem cell biology.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks

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Call for proposal

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(opens in new window) HORIZON-MSCA-2023-DN-01

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Coordinator

EUVITRO SLU
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 503 942,40
Address
CARRER DE BALMES 236
08006 BARCELONA
Spain

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Este Cataluña Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (10)

Partners (4)

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