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Is there mechano in Mechanochemistry?

Project description

Challenging the core concept of mechanochemistry

With applications in all realms of synthetic chemistry, mechanochemistry is an emerging field with vast potential. It eliminates the need for conventional solvents, making chemical processes more eco-friendly. The concept is based on the premise that colliding milling balls transfer mechanical energy to reactants, thus initiating their reactivity. Challenging this concept, the ERC-funded Mecha-NO-Chem project contends that most chemical reactions designated as mechanochemical are, in fact, initiated by intensive mixing under thermal control and not by the absorption of mechanical energy. Therefore, it aims to establish a new classification for ostensibly mechanochemical reactions, categorising them based on mixing as well as thermal and mechanical energy. To do so, it will create methods to isolate and quantify these three parameters.

Objective

At present, mechanochemistry is transferring an ever-growing number of chemical reactions from conventional wet-chemical procedures into the solid-state environment of ball mills. As an electrified and largely solvent-free synthesis concept, it addresses the call for greater sustainability in chemistry, while simultaneously unrevealing a widely unexplored academic frontier with often markedly different product selectivities.
Applied in organic and inorganic chemistry, in the synthesis of polymers and biomolecules, the idea almost always revolves around the concept that colliding milling balls transfer mechanical energy to reactants, thereby initiating their reactivity. This concept is reflected in the definition of mechanochemistry by IUPAC as 'chemical reactivity initiated by the absorption of mechanical energy'.
This project challenges the core of this definition, hypothesizing that the majority of what is denoted as mechanochemical is not initiated by the absorption of mechanical energy at all. This project is groundbreaking as it aims to change the self-conception of a discipline.
It develops a new classification for seemingly mechanochemical reactions - the triangle of mechanochemistry, which categorizes reactions based on mixing, thermal- and mechanical energy. I hypothesize that most reactions designated as mechanochemical are not driven by mechanical energy, but by intensive mixing, still operating under thermal control near room temperature.
I will develop methods to isolate and quantify these three parameters in mechanochemical reactions and locate latter in the triangle of mechanochemistry.
This project will explore the reasons behind mechanochemical reactivity challenging the fundament a whole discipline is built on its current definition. Precisely this knowledge on the underlying principles of mechanochemistry is pivotal to sophisticate and foster reliability within this expanding discipline and to remove it from the realm of black-box chemistry.

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Topic(s)

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HORIZON-ERC - HORIZON ERC Grants

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Call for proposal

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(opens in new window) ERC-2024-COG

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Host institution

RUHR-UNIVERSITAET BOCHUM
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 999 605,00
Address
UNIVERSITAETSSTRASSE 150
44801 Bochum
Germany

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Region
Nordrhein-Westfalen Arnsberg Bochum, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 999 605,00

Beneficiaries (1)

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