Objective
Breast cancer is the most prevalent cancer globally, affecting 13% of women in their lifetime. For those women who undergo a mastectomy, breast reconstruction has become an integral part of their treatment. While two stage implant-based reconstructions are by far the most common procedure, they are sub-optimal: They suffer from high complication rates and low patient satisfaction. The first stage of implant based reconstructions involves the insertion of a tissue expander, silicone implants gradually inflated below the skin over several weeks to induce new skin growth. Improving patient outcomes and patient satisfaction requires a deep understanding of the biomechanical mechanisms associated with growing new tissue and the challenges associated with predicting its future behaviour. However, the lack of adequate in vivo techniques to evaluate and predict the amount of tissue growth is an obstacle to effective surgical planning.
BreastRecon aims to address these challenges by developing a novel acoustoelastic method which can non-invasively determine key biomechanical parameters. Specific objectives of BreastRecon include (i) the development of a wearable surface wave device for clinical in vivo measurements (ii) the quantification of in vivo tension using the device (iii) the non-invasive determination of tissue growth and (iv) the development of a real-time optimisation procedure for the design of tissue expansion protocols. To achieve these ambitious goals, BreastRecon employs a distinctive combination of acoustoelastic tissue measurements, physics-based machine learning techniques and novel device development.
BreastRecon will initially provide a tool to monitor tissue growth in vivo, offering valuable fundamental insights into growth and remodelling processes. Ultimately, it will advance patient-specific tissue expansions by designing optimum protocols based on individual biomechanical measurements, offering a disruptive breakthrough in reconstructive surgeries.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine surgery
- medical and health sciences clinical medicine oncology breast cancer
- medical and health sciences medical biotechnology implants
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2024-COG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
4 DUBLIN
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.