Project description
Radiotheranostic solutions for solid tumour personalised treatment
Radiotheranostics uses paired diagnostic and therapeutic radionuclide probes to selectively diagnose and treat specific cells, such as cancer, in line with personalised medicine. However, challenges related to logistics, supply chains, regulatory issues, and education/training need to be addressed. In this context, the EU-funded Thera4Care project will develop standardised methods for producing and administering these solutions. The project focuses on creating diagnostic and therapeutic ligands for diseases like solid tumours and seeks to establish a European network of radiotheranostics centres. It will oversee project management, regulatory aspects, preclinical studies, supply chains, clinical trials, AI models, dosimetry, precision imaging components, education, and dissemination. The project will advance radiotheranostics, coordinate scientific initiatives, and improve radionuclide availability.
Objective
Thera4Care represents a large unique consortium, gathering well-established European academic radiotheranostic centres, strong industry partners, European and medical societies focusing on training and education, a patient advocacy group spearheaded by an experienced project management group. Thera4Care aims to establish a European network of radiotheranostics centres able to rapidly develop and implement radiotheranostics tools and solutions to drive precision health. The overarching vision of Thera4Care is to revolutionise radiotheranostics procedures by establishing, implementing, and disseminating standardised scalable methods to produce and efficiently administer key radiotheranostics solutions. Thera4Care focus is on developing diagnostic and therapeutic ligands tailored to key disease areas (such as solid tumours), aligning with the growing significance of multi-modal radiotheranostics solutions dominated by radionuclide-based therapy and companion diagnostics. Thera4Care project is scheduled for 5 years and consists of 9 work packages. WP1 handles Project Management, WP2 focuses on Regulatory aspects, WP3 plans Preclinical studies, WP4 provides Supply chain, WP5 develops Clinical Trials, WP6 generates AI models, WP7 focuses on Dosimetry, WP8 develops Precision Imaging components, while WP9 focuses on Education and Dissemination. Thera4Care will advocate for the progress of radiotheranostics, with the goal of increasing medical knowledge and enhancing treatment efficacy for improved patient outcomes. Concurrently, aims to coordinate scientific initiatives across European landscapes, leveraging a comprehensive and multimodal approach to cancer therapy applicable to various cancer types. Lastly, will work on the establishment of sustainable supply and production networks and the upscaling of production methodologies and supply chains across the public and private sectors, to enhance the availability of radionuclides.
Fields of science
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
Programme(s)
- HORIZON.2.1 - Health Main Programme
- HORIZON.2.1.7 - Innovative Health Initiative
Funding Scheme
HORIZON-JU-RIA - HORIZON JU Research and Innovation ActionsCoordinator
20123 Milano
Italy
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Participants (25)
1138 Budapest
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
3508510 Haifa
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
752 28 Uppsala
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45147 Essen
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81677 MUNCHEN
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1070 Anderlecht
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28046 MADRID
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
28007 Madrid
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3015 GD Rotterdam
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49100 Angers
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1060 Wien
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1160 Bruxelles / Brussel
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00168 Roma
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1160 Bruxelles / Brussel
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00138 Roma
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
2200 Kobenhavn
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
3650 OLSTYKKE
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223 70 LUND
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
00150 Helsinki
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
41327 GOTEBORG
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
94230 CACHAN
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
4817 ZK BREDA
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1142 Budapest
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
98121 Seattle
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405 30 Goeteborg
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Partners (4)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
5232 Villigen Psi
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1085 Budapest
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
HP8 4SP CHALFONT ST GILES
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
60661-3671 Chicago
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