Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS

2D Nano Hybrid Systems: interfacing biomolecular motors with nanopores in 2D materials

Project description

Advancing nanotechnology applications in biomedical science

The electroconductive and mechanical properties of graphene and other 2D materials have been instrumental in nanotechnology applications. These materials can serve as membranes to create nanopore devices and sensors for single molecule analysis. The EU-funded 2D-NanoHyb project proposes to combine biological inspiration and nanoscale engineering to develop new methods for attaching biomolecular motors, like DNA helicase, to 2D nanopores. This integration would allow for active control over the movement of single molecules and ions through the nanopores. The resulting nano-hybrid technology promises transformative applications in nanobiotechnology, environmental sensing, and diagnostics.

Objective

Interfacing the solid-state electronics with biological systems has been a long-standing challenge in nanobiotechnology. Creating nanobio hybrids would enable harnessing the remarkable capabilities offered by solid-state materials and biological molecules, such as proteins, enzymes, DNA etc., at the same time. Two-dimensional (2D) materials are among the most prospective building blocks for future-generation electronic and biosensing devices due to their exceptional optoelectronic and mechanical properties combined with their atomic thickness. Their ultimate thinness has been considered as a remarkable advantage for nanopore-based sensing, and they have been widely investigated as 2D solid-state nanopore platforms for single-molecule sensing. The goal of this proposal is to push further the development of 2D nanopores by developing new protocols for creating interfaces between 2D materials and biomolecular motors. Attaching the enzyme motor, such as DNA helicase, to a nanopore made in 2D material would introduce an active control in nanofluidic transport of single-molecules and ions. Such hybrid platforms presents a step forward in uniting biological inspiration and nanoscale engineering, offering unprecedented levels of control, precision, and versatility at the nanoscale. The future direction holds promise across a wide spectrum of applications, from fundamental scientific research to transformative technologies that could impact fields as diverse as nanobiotechnology, personalized medicine and diagnostics, environmental sensing, nanorobotics, and many more.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

You need to log in or register to use this function

Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

See all projects funded under this funding scheme

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-WIDERA-2023-TALENTS-02

See all projects funded under this call

Coordinator

INSTITUT ZA FIZIKU
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 146 049,60
Address
BIJENICKA CESTA 46
10000 Zagreb
Croatia

See on map

Region
Hrvatska Grad Zagreb Grad Zagreb
Activity type
Research Organisations
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Partners (1)

My booklet 0 0