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Genomic applications for laboratory Diagnostics supported by Artificial Intelligence

Project description

AI-powered metagenomic potential use for advanced diagnostics

Artificial Intelligence (AI) is revolutionising diagnostic processes, leading to the advancement of personalised medicine. With the support of the Marie Skłodowska-Curie Actions programme, the GenDAI project will leverage metagenomic potential for advanced diagnostics, contributing to the development of personalised treatments. It aims to create an AI-supported medical diagnostics platform for microbiome profiling, generate new metagenomic datasets for patients with inflammatory bowel disease, and develop the GenDAI Diagnostics Workflow, focusing on implementing a fully automated data processing pipeline. Additionally, the project will establish a robust, cloud-based foundation for platform development, incorporating advanced data management and security infrastructure for long-term archiving (GenDAI Safe). It will also identify biomarkers, characterising microbiome profiles, and delivering user-friendly clinical reporting.

Objective

GenDAI will leverage metagenomic potential to deliver powerful diagnostic results facilitating the development of Personalized Medicine, addressing assay research and development as well as productive clinical diagnostics in a comprehensive way by creating a highly innovative medical diagnostics platform that supports microbiome profiling with novel biomarkers using Artificial Intelligence (AI). This innovative platform will allow clinicians to assess and monitor patients while complying with strict regulatory requirements of laboratory diagnostics. Ultimately, GenDAI will contribute to accelerate conversion of innovative ideas and technology solutions into breakthroughs in medical analyses services.

Delivery of GenDAI tangible outputs will be driven by the following Research and Innovation Objectives: a) Create new metagenomic datasets containing microbiome samples from stool of patients under informed consent suffering from inflammatory bowel disease (IBD); b) Develop and integrate the GenDAI Diagnostics Workflow, focusing on implementing a fully automated data processing pipeline; c);Provide a robust, cloud-based foundation for the development of the platform that integrates advanced data management and knowledge infrastructure focusing on security, reproducibility and long-term archiving (GenDAI Safe); d) Develop and improve AI methods to identify relevant biomarkers and classify corresponding metagenomic sequences in order to characterise microbiome profiles to provide a personalised diagnostic result of patients state of health (GenDAI Discovery); e) Deliver innovative visual user interfaces and interactive clinical reporting (GenDAI Interactive Reporting) and f) Deliver the marketable, regulatory compliant GenDAI technology and tool suite.

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HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges

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Call for proposal

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(opens in new window) HORIZON-MSCA-2023-SE-01

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Coordinator

FTK-FORSCHUNGSINSTITUT FUR TELEKOMMUNIKATION UND KOOPERATION EV
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 276 000,00
Address
WANDWEG 3
44149 Dortmund
Germany

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Region
Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt
Activity type
Research Organisations
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Total cost

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Participants (5)

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