Project description
Real-time cancer diagnosis and treatment with light and plasma
Endoscopy is crucial for diagnosing gastrointestinal disorders, but it still relies on histopathology for cancer diagnosis, causing delays and high costs. With this in mind, the EIC-funded MULTISCOPE project addresses this challenge with a revolutionary photonic technology. By combining optical biopsy and cold atmospheric plasma therapy, MULTISCOPE introduces a dual-function device capable of real-time, in vivo diagnosis and immediate therapeutic intervention. The device harnesses spatiotemporal control of light in advanced multimode fibres, overcoming previous limitations. Initially focused on gastrointestinal endoscopy, the technology aims to transform medical diagnostics across various fields, offering reliable, instantaneous diagnoses and targeted cancer treatments without the need for invasive procedures.
Objective
"MULTISCOPE introduces a revolutionary photonic technology that represents a significant advancement in the field of optical diagnostics and therapy. Our approach is based on cutting-edge research into pulse propagation within nonlinear complex structures. We are developing an endoscopic device that seamlessly combines optical biopsy and cold atmospheric plasma treatment. This dual-functionality device harnesses the spatiotemporal control of powerful light in multimode fibers, which were previously overlooked due to concerns about excessive light destructuring. We leverage the remarkable progress in the development of the latest optical fibers and in the precise control of light within multimode guides, enabling us to harness the power of plasma, the fourth state of matter. Initially, our focus is on gastrointestinal (GI) endoscopy, but our ultimate goal is to extend this technology to all areas of medical diagnostics where there is a pressing need for reliable tools for ""optical biopsy"" and ""instant pathology."" These tools are crucial for real-time diagnosis but have not yet reached the level of trustworthiness required for widespread use. Endoscopy is a vital tool for diagnosing and treating GI disorders, offering a safe and effective approach. However, the current standard of care still relies on histopathology for conclusive cancer diagnosis. This leads to significant delays in initiating treatment and incurs high costs. Our project is set to transform this landscape by bringing to life the long-anticipated concept of real-time, in-vivo optical diagnosis, often referred to as ""optical biopsy"". Our groundbreaking approach seamlessly integrates endoscopic capabilities with cold atmospheric plasma therapy, which employs controlled plasma jets to precisely target and eliminate cancer cells by inducing cellular apoptosis. By combining plasma therapy with optical biopsy, we not only provide real-time diagnosis but also offer immediate therapeutic intervention."
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2024-PATHFINDEROPEN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
00185 Roma
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.