Liver Titanium Dioxide Toxicology: Investigating the Mechanisms of Liver Toxicity Induced by the Food Additive E171 (Titanium Dioxide, TiO2) Using In Vitro, In Vivo, and In Silico Approaches

Project Information

LiTiTox

Grant agreement ID: 101211977

DOI

10.3030/101211977

EC signature date 14 April 2025

Start date 1 October 2025

End date 30 September 2027

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 200 400,00

Coordinated by

VRIJE UNIVERSITEIT BRUSSEL
Belgium

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Deliverables

Data Management Plan (1)

Data Management Plan

A comprehensive Data Management Plan (DMP) will be developed at the start of the project in full alignment with the European Commission's Open Science agenda and the FAIR data principles. All datasets generated from in vitro, in vivo, and in silico experiments will be accompanied by comprehensive metadata and deposited in public repositories to promote easy discovery and accessibility. Data will be provided in formats such as CSV or FASTA to ensure compatibility with other datasets and enhance interoperability. Raw transcriptome and proteome data will be made publicly available through the Sequence Read Archive (SRA) at NCBI. In vivo studies will strictly adhere to the ARRIVE guidelines, ensuring that ethical considerations and experimental protocols are transparently shared to facilitate reproducibility. The project will prioritize publication in Gold Open Access journals to ensure unrestricted and immediate access to research findings, contributing to the open science.