Project description
Treating infected wounds at the source
Infections in complex wounds often lead to prolonged treatment, hospital stays, and long-term complications. Supported by the Marie Skłodowska-Curie Actions programme, the INTROS project is tackling this head-on by training a new generation of scientists to develop smart materials and tools for early diagnosis and infection prevention. Through a multidisciplinary doctoral network, INTROS is advancing nano- and micro-scale delivery systems, hydrogel-based patches, and biodegradable sensors that detect infection and deliver targeted therapies. These solutions aim to reduce inflammation, support healing, and minimise scarring. The project also prioritises scalable manufacturing and real-world testing in lab and ex vivo wound models. By combining cutting-edge science with hands-on industry training, INTROS is transforming the way we treat wounds.
Objective
The INTROS project, as multi- and interdisciplinary doctoral network, will develop diagnostic and prevention strategies for acute complex wounds that are at risk of infection. Infections represent a significant challenge, as they often require prolonged treatment and may even result in extended hospital stays. All this is associated with considerable burden to clinics and patients as well as financial costs. To address this issue, the doctoral candidates and consortium partners dedicate their efforts in creation of early diagnostic methods that can effectively detect infection and/or facilitate the direct application of advanced antimicrobial dressings and innovative formulations following burn or surgical procedures. Additionally, the (bio)materials will be designed to prevent inflammation, promote healing and regeneration, thereby reducing the risk of infection and its associated complications such as scarring and impairments. The developed systems will consist of innovative nano-/micro-sized delivery systems, biodegradable and-compatible electrical sensors or patches based on hydrogels, bacterial nanocellulose and polyurethanes as well as biologically active extracellular vesicles. This will be supported by extensive biocompatibility and efficacy testing in vitro, in vivo and especially in ex vivo wound models as well as in-depth physicochemical characterisation. Special emphasis will be on the scale-up to industrial levels and manufacturing towards GMP conditions already during the project’s lifetime. INTROS will contribute to bringing forward a new generation of young scientists by creating a research and training network for 8 Doctoral Candidates, equip them with multidisciplinary skills from biomaterials, nanotechnology, pharmaceutical chemistry and technology, biochemistry and material science. Combined with extensive complementary soft/transferable skills, INTROS will enable them to take leading roles in industry and academia in the European community.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been validated by the project's team.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been validated by the project's team.
- natural sciences biological sciences biochemistry
- engineering and technology nanotechnology
- natural sciences chemical sciences polymer sciences polyurethane
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- engineering and technology industrial biotechnology biomaterials
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN-ID - HORIZON TMA MSCA Doctoral Networks - Industrial Doctorates
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-DN-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
66802 UBERHERRN
Germany
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.