Project description
Advancing fertility through science
Infertility affects about one in six women globally, often because of problems in the uterus, a vital yet underexplored organ in conception. Assisted reproduction technology (ART) procedures help many couples, but pregnancy success rates remain limited when uterine function is compromised. Supported by the Marie Skłodowska-Curie Actions programme, the TULIP project will study how the uterus’ glycosylation patterns and microbiota affect fertility. The findings will shed light on the biological processes that make conception possible. Additionally, the project will train early-stage researchers and develop less invasive diagnostic tools. The goal is to improve ART outcomes and deepen our understanding of reproductive health.
Objective
Conception and pregnancy are both complex processes, with approximately 1 in 6 women worldwide experiencing infertility, often due to compromised uterine function, the organ designed solely for sustaining life. However, these dysfunctional uterine mechanisms remain not fully understood. Moreover, assisted reproduction technologies (ART) are employed to address infertility, with 5% of newborns in Europe conceived through ART. Nevertheless, the use of ART still results in low pregnancy success rates, with uterine dysfunction being a significant factor. This underscores the importance of the uterus in medical research, which has previously received little attention for its pivotal role in the journey towards motherhood.
The TULIP consortium focuses on emerging topics, including the interplay between glycosylation and the microbiota within the uterus in relation to fertility. This interdisciplinary consortium comprises experts from six European countries, representing eight academic and four industry partners, and uniquely combines specialists in female reproductive medicine with researchers in glycobiology, microbiota studies, genomics, and data science. We aim to achieve a breakthrough in understanding the core biological aspects of conception, thereby fostering accurate and less invasive diagnostic methods that lead to more effective and personalised implementation of ART through pioneering tools designed to overcome poor reproductive outcomes.
This breakthrough will be achieved by engaging 33 early-stage researchers in a collaborative interdisciplinary training and research programme. The programme seeks to emphasise scientific knowledge while fostering entrepreneurial and transferable skills over the 48-month project period. Collectively, these efforts enhance diagnostic and therapeutic tools to improve reproductive success in both natural and assisted conception while reinforcing inter-sectoral and interdisciplinary collaborative networks and the R&I capacity.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- social sciences sociology demography fertility
- medical and health sciences clinical medicine obstetrics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-SE-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
171 77 STOCKHOLM
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.