Objective
ARMOR addresses a major challenge in modern medicine: chronic biofilm-associated infections, which are highly resistant to antibiotics and closely linked to antimicrobial resistance. The project will develop a new generation of safe, biomimetic nanovesicles inspired by bacterial outer membrane vesicles that can penetrate biofilms and deliver therapeutics directly to the infection site. By combining detoxified bacterial membrane components with synthetic lipids and responsive materials, ARMOR aims to create programmable vesicles that release their cargo only under biofilm-specific conditions such as acidic pH or bacterial enzymes. The platform will integrate multiple antimicrobial strategies, including antibiotics, antimicrobial peptides, enzymes, and light- and ultrasound-activated agents, to achieve targeted and synergistic biofilm eradication. A distinctive feature of ARMOR is its closed design-build-test-learn framework, in which artificial intelligence, advanced imaging, and quantitative in vitro and in vivo data are combined to iteratively optimise vesicle design, delivery, efficacy, and safety. The project brings together an international, interdisciplinary, and intersectoral consortium spanning academia and industry across Europe and beyond. Through structured staff secondments, shared training, and joint research activities, ARMOR will promote deep transfer of knowledge and build durable collaboration networks. ARMOR is expected to deliver validated preclinical lead formulations, AI-enabled optimisation workflows, and scalable approaches for vesicle production, stabilisation, and quality control. In the longer term, the project will strengthen Europe’s capacity to develop precision anti-infective therapies, reduce reliance on conventional antibiotics, and improve the management of chronic biofilm infections and antimicrobial resistance.
Fields of science (EuroSciVoc)
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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HORIZON.1.2.3 - Strengthening Human Resources and Skills Development across the European Research Area
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2026-SE-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
00133 Roma
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.