Clinical consequences of mannose binding lectin dysfunction.

Project Information

MBLUKP

Grant agreement ID: 11868

Project closed

Start date 1 January 2005

End date 31 December 2005

Funded under

• Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006

Total cost No data

EU contribution € 40 000,00

Coordinated by

POLISH MOTHERS MEMORIAL HOSPITAL- RESEARCH INSTITUTE
Poland

Objective

Infection remains an important cause of morbidity and mortality in neonates. We have established that MBL defects can influnce the rate of infection in this patient population. Therefore if we understood more about importance and mechanisms of this MBL dys function we could potentially modify our approach to managing neonatal infection. This project is a logical extension of work performed while I was a Marie Curie Individual Reseach Fellow. The basis of this project stems from recent work which shows that c omplement activating capacity of MBL is related to levels of MASP-2, an MBL associated serine protease. The proposed study will explore the relationship between MASP-2 activity and susceptibility to infection. This work will be complemented by genetic stud ies relating MASP-2 genotype and MASP-2 levels. The results of this project will directly inform on the role of MBL- MASP in neonatal susceptibility to infection. In addition it will allow me to reintegrate back to Poland and facilitate two way scientific interactions between Poland and the UK.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

• social sciences › sociology › demography › mortality
• natural sciences › biological sciences › microbiology › virology
• medical and health sciences › basic medicine › immunology
• medical and health sciences › health sciences › infectious diseases › RNA viruses › HIV
• medical and health sciences › clinical medicine › oncology

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Programme(s)

• FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006

Topic(s)

• MOBILITY-4.1 - Marie Curie European Reintegration Grants (ERG)

Call for proposal

FP6-2002-MOBILITY-11
See other projects for this call

Funding Scheme

ERG - Marie Curie actions-European Re-integration Grants

Coordinator

POLISH MOTHERS MEMORIAL HOSPITAL- RESEARCH INSTITUTE

• EU contribution: No data
• Address: Rzgowska 281/ 289 Street ; LODZ ; Poland
• Total cost: No data