Skip to main content
Vai all'homepage della Commissione europea (si apre in una nuova finestra)
italiano it
CORDIS - Risultati della ricerca dell’UE
CORDIS
Contenuto archiviato il 2024-05-29

Clinical consequences of mannose binding lectin dysfunction.

Obiettivo

Infection remains an important cause of morbidity and mortality in neonates. We have established that MBL defects can influnce the rate of infection in this patient population. Therefore if we understood more about importance and mechanisms of this MBL dys function we could potentially modify our approach to managing neonatal infection. This project is a logical extension of work performed while I was a Marie Curie Individual Reseach Fellow. The basis of this project stems from recent work which shows that c omplement activating capacity of MBL is related to levels of MASP-2, an MBL associated serine protease. The proposed study will explore the relationship between MASP-2 activity and susceptibility to infection. This work will be complemented by genetic stud ies relating MASP-2 genotype and MASP-2 levels. The results of this project will directly inform on the role of MBL- MASP in neonatal susceptibility to infection. In addition it will allow me to reintegrate back to Poland and facilitate two way scientific interactions between Poland and the UK.

Campo scientifico (EuroSciVoc)

Argomento(i)

Invito a presentare proposte

FP6-2002-MOBILITY-11
Vedi altri progetti per questo bando

Meccanismo di finanziamento

ERG - Marie Curie actions-European Re-integration Grants

Coordinatore

POLISH MOTHERS MEMORIAL HOSPITAL- RESEARCH INSTITUTE
Contributo UE
Nessun dato
Costo totale
Nessun dato