Objective
Infectious disease is the leading cause of morbidity and mortality in developing countries, and one of the leading causes worldwide. The twentieth century witnessed spectacular decays in infectious disease. Vaccines have eliminated smallpox, and have dramatically reduced the incidence of childhood diseases. A major concern is that the success of vaccination and other control measures is far from uniform. Interventions aimed at reducing tuberculosis, malaria, and several respiratory and diarrhoeal diseases have generally failed.
The management of recurrent infections is a major global challenge for biomedical science and public health in the twenty-first century. Recurrent infections occur as pathogens evolve a variety of ways to circumvent immunity: persisting at reduced activity (Mycobacterium tuberculosis, Plasmodium spp), or confusing the immune system by change in appearance (influenza virus, respiratory syncytial virus). Empirical relationships between such elaborate host-pathogen interactions and the observed epidemiological patterns are difficult to deduce.
Simple mathematical models are useful conceptual tools, but the potential for unwanted artefacts increases dramatically as each layer of complexity is introduced. These will be paralleled by more flexible computer models, combining the dynamics of infection, immunity, and pathogen ecology. Intervention design will be explored in the presence of reinfection, space, stochasticity, and resonance effects.
Many high impact diseases (tuberculosis, malaria and respiratory diseases) are considered in depth, and the results given a broad perspective. Theoretical models will be developed in coordination with laboratory and fieldwork, with two complementary roles: (1) assess the epidemiological impact of mechanisms of infection and immunity; (2) set targets for future interventions. The control of complex infectious disease problems is currently a major challenge where integrated approaches are in great demand.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences health sciences infectious diseases malaria
- medical and health sciences health sciences public health epidemiology
- medical and health sciences health sciences infectious diseases RNA viruses influenza
- medical and health sciences clinical medicine pneumology tuberculosis
- medical and health sciences health sciences infectious diseases RNA viruses coronaviruses
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-8
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LISBOA
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.