Objective
The RETHINK project will produce an impact assessment report on toxicity testing in the mini-pig as an alternative approach that can contribute to the replacement, refinement and reduction of animal testing (3Rs). The pig is close to man in terms of ana tomy, physiology and biochemistry and in consequence is an attractive model for safety evaluation and biomedical research, which may permit the replacement of dogs and monkeys and the more efficient and predictive use of biological resources and animal l ife. This promising approach is deserving of objective evaluation and this is the propitious moment, as legislation places greater emphasis on alternative approaches in safety evaluation (eg REACH initiative), and as toxicogenomics begins to make a cont ribution to safety issues. If the minipig is to provide a valid, realistic and robust alternative approach for use in the regulatory testing of new medicines and chemicals, while contributing to the 3Rs, there are issues that must be addressed in six div erse areas: (i) animal welfare, (ii) ethics, (iii) new medicines and chemicals development, (iv) validation of animals models in safety evaluation, (v) genomics and emerging technologies, and (vi) economic impact and overview issues. The Steering G roup (SG) of consortium members will assemble Working Groups (WG¿s) of recognised experts in each topic area and will provide WG¿s with methods to define a hierarchy of issues and develop responses. WG¿s will review and summarise the available body of kn owledge for their topic and prepare conclusions and recommendations, including identification of gaps in knowledge where further research is required, and technical gaps presenting obstacles to the use of minipigs. The WG documents will be finalised for a plenary meeting of experts, followed by editing into the final Impact Assessment report. The Impact Assessment will be made publicly available and disseminated to relevant stakeholders
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- agricultural sciences animal and dairy science domestic animals
- medical and health sciences basic medicine physiology
- medical and health sciences basic medicine toxicology
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-LIFESCIHEALTH-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EVREUX
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.