Project description
Rebuilding damaged cartilage for pain-free joints
Cartilage tissue is necessary for pain-free movement of joints. This thin layer of highly specialised tissue covers the end of bones in the joints where it functions as a load absorbing cushion with invincible lubrication properties. Unfortunately, cartilage has limited self-renewal capacity because of the lack of vessels and nerves spanning the tissue. Therefore, cartilage damage due to trauma or osteoarthritis cannot be inherently healed but must be repaired surgically. The EIC-funded RePace project has developed an innovative implant that facilitates quick rehabilitation and restores the original functionality of the tissue. The generated implant consists of a biodegradable matrix that provides mechanical support for fast rehabilitation back to pain-free activity alongside long-term results and quality of life improvement.
Objective
A healthy layer of articular cartilage at the end of bones in joints is essential for painless movement. When cartilage is damaged, it has minimal innate regenerative properties and there is no effective medical cure. Cartilage damage seriously reduce quality of life and has severe economic impact since loss of cartilage leads to osteoarthritis (OA) that causes hundreds of billions of Euros healthcare and related costs annually.
Many attempts have been made to restore joint surface cartilage, but the tissue has shown to be extremely difficult to rebuild.
Askel has developed a unique way to rebuild joint surfaces for pain-free movement. COPLA is a biodegradable implant that creates a weight-adaptive microenvironment in the damaged site enabling quick rehabilitation and cartilage regeneration to prevent OA.
COPLA will become the Gold Standard for early cartilage repair with rapid recovery and long-term results, ensuring pain-free movement, high quality of life and prevention of OA.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine physiotherapy
- medical and health sciences medical biotechnology implants
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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HORIZON.3.1.2 - The Accelerator
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2021-ACCELERATOROPEN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
00530 Helsinki
Finland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.