Microbiome Abundance Profiling: Precision microbiome profiling for insights into human health & research

Informations projet

Perseus MAP

N° de convention de subvention: 190119214

DOI

10.3030/190119214

Projet clôturé

Date de signature de la CE 17 Juin 2022

Date de début 1 Octobre 2021

Date de fin 30 Septembre 2023

Financé au titre de

• The European Innovation Council (EIC)

Coût total

€ 3 575 740,00

Contribution de l’UE

€ 2 500 000,00

Coordonné par

PERSEUS BIOMICS
Belgium

Periodic Reporting for period 2 - Perseus MAP (Microbiome Abundance Profiling: Precision microbiome profiling for insights into human health & research)

Période du rapport: 2022-10-01 au 2023-09-30

Résumé du contexte et des objectifs généraux du projet

Perseus Biomics is developing ground breaking microbiome analysis services and devices, with the aim to spark a data driven revolution in the microbiome field. Generating high quality microbiome analysis will allow to uncover the dynamic microbiome nature, as it impacts our daily lives. Perseus Biomics will make such high quality microbiome analysis available to patients and researchers in the timeframe of hours, enabling action on the highly dynamic and personalized nature of the human microbiomes, with applications in diagnostics and therapeutics. At the core of this development within the EIC project lies the accelerated prototyping and industrialization of a custom microbiome analysis device and associated protocols and consumables, for global placement of the Perseus Biomics technology.

Travail effectué depuis le début du projet jusqu’à la fin de la période considérée dans le rapport et principaux résultats atteints jusqu’à présent

Perseus Biomics has entered a rapid design and prototyping cycle, with a first prototype of the Perseus Biomics microbiome analyzer available in the Perseus Biomics headquarters, undergoing benchmarking studies. Early in the project, a key decision was made to build on off-the shelf components for the construction of the prototype, and this has allowed us to reach a functional prototype well within the foreseen timeframe. This prototype includes automated sample handling capacities and automated sample analysis of multiple microbiomes in a single run. The associated consumables have gone through the first step of industrialization, and are available for use on the prototype microbiome analyser. This included stability studies and formulation of the components of the Perseus Biomics chemoenzymatic process, the DNA deposition consumables and client side microbiome sampling consumables. Bespoke remote monitoring of the device is implemented, supporting global placement and servicing of the devices.

Progrès au-delà de l’état des connaissances et impact potentiel prévu (y compris l’impact socio-économique et les conséquences sociétales plus larges du projet jusqu’à présent)

The rapid construction of the Microbiome DNA analyzer allows Perseus Biomics to accelerate our rapid microbiome analysis pipeline.
The prototype devices will allow placement of Perseus Biomics devices at selected users within the next years, supporting rapid internationalization and market validation.
The data generated on the devices will serve as key enable to support market entry by Perseus Biomics, as we enter a market that is heavily dominated by DNA sequencing players and their devices.