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The first true minimally-invasive Spinal Fusion System

Project description

Miniature screw-less implant-based spinal fusion procedure

Spinal fusion involves the surgical connection of two or more vertebrae to eliminate motion. The company has developed an alternative to the current screws and rods used for spinal stabilisation. While current procedures use the screws and rods to create an artificial bridge, zLOCK utilises our spine's natural bridge for stability. Funded by the European Innovation Council, the zLOCK project aims to clinically validate and commercialise a minimally invasive procedure using its bendable implant that adjusts to the patient's anatomy. The porous texture of the implant facilitates bone growth and fusion. Moreover, implant placement requires only a minimally invasive skin incision, allowing the procedure to be performed in an outpatient setting.


Over 1M spinal fusion procedures performed annually worldwide. Current spinal fusion procedures are highly invasive: they are based on building “screw-bridges”, connected by metal rods stabilizing motion between vertebrae. There are no effective treatments in the market that substitute the current invasive implants. zLOCK is a small implant that resolves spinal fusion by eliminating the need for screws and rods. zLOCK minimizes the invasiveness of procedures through a percutaneous approach, where only a small skin incision is required for implant placement, making it suitable for outpatient procedures. zLOCK can revolutionize spinal fusion standard clinical practice and the market. The implant value propositions have been confirmed in a first in human trial. With the EIC Accelerator project, ZygoFix will complete the necessary upgrades and clinical validation activities, achieve CE-mark and accelerate the time-to- market of zLOCK.



Net EU contribution
€ 2 220 050,00
17 t’helet street, misgav business park
2017400 Misgav

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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 963 950,00