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A minimally invasive and durable endograft fastening solution for Abdominal Aortic Aneurysm (AAA)

Project description

Safer implant for endovascular aneurysm repair

Abdominal aortic aneurysms (AAA) are a common medical condition affecting millions of people worldwide each year. Several risk factors contribute to the development of AAA, including smoking, high blood pressure and a family history of the condition. Early detection and treatment are crucial for preventing AAA rupture, which can be life-threatening. Improving treatment is a priority. In this context, the EIC-funded aortoseal project will develop an innovative implant providing a safer, low-risk treatment option that combines the benefits of open surgery with the safety and efficacy of endovascular aneurysm repair. By reducing the need for open surgery and secondary interventions, the project expects to improve patient outcomes and reduce healthcare costs across the EU.

Objective

Abdominal aortic aneurysm (AAA) is a focal enlargement of the abdominal aorta below the renal arteries and is found in up to 4 million patients globally each year. If left untreated it can be fatal, so it is imperative to provide early, prophylactic treatment before a rupture occurs. The available treatment options are far from optimal: open surgery is a durable, life-long, but high-risk solution. The alternative, EVAR, has lower immediate risks, but is a shorter-term solution and requires continual monitoring and secondary interventions.
We have developed Aortoseal, a fixation and sealing implant for endovascular aneurysm repair that combines the best of both worlds: the stability of an open, sutured repair and the safety and low-risk delivery of EVAR. Aortoseal will reduce the need for open surgery, the need for secondary procedures and time in the hospital, all leading to improved patient outcomes and projected healthcare savings over a 10 year period of ~9 bn across the EU.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance

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Call for proposal

(opens in new window) HORIZON-EIC-2022-ACCELERATOR-01

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Coordinator

ENDORON MEDICAL LTD.
Net EU contribution
€ 2 499 999,00
Address
21 ATIR YEDA
4464316 Kfar Saba
Israel
SME
Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
€ 6 046 607,50