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A minimally invasive and durable endograft fastening solution for Abdominal Aortic Aneurysm (AAA)

Project description

Safer implant for endovascular aneurysm repair

Abdominal aortic aneurysms (AAA) are a common medical condition affecting millions of people worldwide each year. Several risk factors contribute to the development of AAA, including smoking, high blood pressure and a family history of the condition. Early detection and treatment are crucial for preventing AAA rupture, which can be life-threatening. Improving treatment is a priority. In this context, the EIC-funded aortoseal project will develop an innovative implant providing a safer, low-risk treatment option that combines the benefits of open surgery with the safety and efficacy of endovascular aneurysm repair. By reducing the need for open surgery and secondary interventions, the project expects to improve patient outcomes and reduce healthcare costs across the EU.

Objective

Abdominal aortic aneurysm (AAA) is a focal enlargement of the abdominal aorta below the renal arteries and is found in up to 4 million patients globally each year. If left untreated it can be fatal, so it is imperative to provide early, prophylactic treatment before a rupture occurs. The available treatment options are far from optimal: open surgery is a durable, life-long, but high-risk solution. The alternative, EVAR, has lower immediate risks, but is a shorter-term solution and requires continual monitoring and secondary interventions.
We have developed Aortoseal, a fixation and sealing implant for endovascular aneurysm repair that combines the best of both worlds: the stability of an open, sutured repair and the safety and low-risk delivery of EVAR. Aortoseal will reduce the need for open surgery, the need for secondary procedures and time in the hospital, all leading to improved patient outcomes and projected healthcare savings over a 10 year period of ~9 bn across the EU.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance

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Call for proposal

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(opens in new window) HORIZON-EIC-2022-ACCELERATOR-01

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Coordinator

ENDORON MEDICAL LTD.
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 499 999,00
Address
21 ATIR YEDA
4464316 Kfar Saba
Israel

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 6 046 607,50
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