Project description
Next-generation aorta patches for cardiovascular surgery
Aortic diseases are a common type of cardiovascular disease that affect the aorta, the main artery that delivers blood from the heart to the rest of the body. When a region of the aorta is weakened, it is called an aneurysm and requires surgery and repair. The EIC-funded AORTYX project aims to develop a next generation device that mimics the environment of the aorta and supports tissue regeneration. The device is adhesive, bioresorbable and can be used during surgery to treat aortic dissections. Unlike currently employed rigid stents, the AORTYX solution is viscoelastic and provides definitive healing of the aorta. As such, it is expected to assist cardiovascular surgeons, improve patient clinical outcome, and reduce associated healthcare costs.
Objective
Aortyx has developed a biomimetic bioresorbable adhesive patch to treat aortic dissections. It is inserted in the aorta through a femoral access using an endovascular catheter and a deployer. The patch adheres to the aortic tear, stopping false lumen blood flow, and promotes natural repair and biointegration thanks to its patented microstructure and viscoelasticity. Current endovascular approaches use rigid grafted stents, that have multiple drawbacks with continuing high mortality rates. These approaches will be replaced by our viscoelastic biomimetic patch that has minimal side-effects and promotes natural repair of the artery. Consequently, our device will reduce AD-associated mortality and improve post-intervention life quality of patients. It will also reduce post-operative stay and increase patient eligibility. We seek EIC Accelerator funding to fund the testing that will prove the scalability of our solution and set us on the path to becoming a global champion of aortic devices.
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Programme(s)
Funding Scheme
HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended FinanceCoordinator
08329 Teia
Spain
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.