Objective Capillary electrochromatography (CEC) combines the high separation efficiency of capillary electrophoresis with high performance liquid chromatography (HPLC) and provides a powerful tool for the separation of a wide range of both neutral and charged components. The proposed integration of this technology and the rotating system of annular chromatography into a continuous annular electrochromatography (CAEC) would increase the throughput up to 20,000 times whilst maintaining an efficiency of more than 100,000 theoretical separation stages per meter. This extends the range of applicability from analytical purposes towards safe and flexible ultra small-scale production of extremely high-value-added products early on in the development stages. The project is thus expected to significantly enhance the sustainability of pharmaceutical and chemical production by providing equipment for highly intensified purification processes. The development of CAEC units as a new generation of extremely flexible high-performance process equipment requires specialised engineering skills and high-precision manufacturing techniques. A wide range of applications will be offered by the development of tailored stationary phases while an improved understanding of the complex processes occurring at different scales is used to model the performance of the CAEC system. An elaborated prototype including on-line sensors and a sophisticated process control concept will be developed and validated under industrial conditions during a demonstration phase. This will guarantee a fast uptake of the projects results and allow for an approved industrial production of the new process equipment within 1 to 2 years after the end of the project. The consortium includes an end user from pharmaceutical industry to ensure the relation to practice as well as highly innovative equipment manufactures capable of producing the required devices and standardised components at affordable costs. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural scienceschemical scienceselectrochemistryelectrophoresis Keywords continuous operation high performance process equipment industrial validation pharmaceutical industry ultra-small scale production Programme(s) FP7-NMP - Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies Topic(s) NMP-2007-3.2-2 - Process Intensification in Chemicals Production Call for proposal FP7-NMP-2007-SMALL-1 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator TECHNISCHE UNIVERSITAT DORTMUND EU contribution € 665 180,00 Address AUGUST SCHMIDT STRASSE 4 44227 Dortmund Germany See on map Region Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Dorota Pawlucka (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all RHEINLAND-PFALZISCHE TECHNISCHE UNIVERSITAT Germany EU contribution € 371 680,00 Address GOTTLIEB DAIMLER STRASSE 67663 Kaiserslautern See on map Region Rheinland-Pfalz Rheinhessen-Pfalz Kaiserslautern, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Berthold Klein (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data TECHNISCHE UNIVERSITAET GRAZ Austria EU contribution € 355 538,00 Address RECHBAUERSTRASSE 12 8010 Graz See on map Region Südösterreich Steiermark Graz Activity type Higher or Secondary Education Establishments Administrative Contact Johannes Khinast (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT FUER MIKROTECHNIK MAINZ GMBH Germany EU contribution € 644 189,00 Address Carl-Zeiss-Str. 18-20 55129 Mainz See on map Activity type Research Organisations Administrative Contact Frank Hainel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MICROINNOVA ENGINEERING GMBH Austria EU contribution € 258 964,00 Address EUROPAPARK 1 8412 Allerheiligen Bei Wildon See on map Region Südösterreich Steiermark West- und Südsteiermark Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Dirk Kirschneck (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data NOVARTIS PHARMA AG Switzerland EU contribution € 131 228,00 Address LICHTSTRASSE 35 4056 Basel See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Berthold Schenkel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data TECHNISCHE UNIVERSITEIT EINDHOVEN Netherlands EU contribution € 196 364,00 Address GROENE LOPER 3 5612 AE Eindhoven See on map Region Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Activity type Higher or Secondary Education Establishments Administrative Contact Paul (P.M.L.O.) Scholte (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data GALILAEUS OY Finland EU contribution € 57 000,00 Address KAIRISKULMANTIE 10 20781 Kaarina See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Piia Hara (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data