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Bottom-up Resolution of Functional Enantiomers from Self-Organised Monolayers

Objetivo

The high throughput identification of resolution systems for industrially important chiral chemicals will be approached using the bottom-up hierarchichal assembly from self-organised chirally nanostructured surfaces and the “Dutch resolution” family method to isolation of enantiomers. Molecular modelling, surface science, supramolecular chemistry and the critically important resolving library design will be used in synergy to develop systems which separate enantiomers and which can be patterned and miniaturised. The preparation of chiral surfaces and the knowledge of chiral discrimination phenomena at the nanoscale will be exploited to use them to template the formation of diastereomers, which in turn will lead to the formation of crystals (whose composition will be determined) containing pure enantiomers. The project’s end goal is a rapid method for the identification of resolving systems for optically active compounds, and would constitute a leap forward for the area.

Convocatoria de propuestas

FP7-NMP-2007-SMALL-1
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Coordinador

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Aportación de la UE
€ 433 876,00
Dirección
CALLE SERRANO 117
28006 Madrid
España

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Región
Comunidad de Madrid Comunidad de Madrid Madrid
Tipo de actividad
Research Organisations
Contacto administrativo
Alberto Sereno Alvarez (Mr.)
Enlaces
Coste total
Sin datos

Participantes (5)