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Natural Products and related Redox Catalysts: Basic Research and Applications in Medicine and Agriculture

Objective

Intracellular redox processes are pivotal for cell survival and proliferation. Redox active natural products, enzymes and their mimics may therefore be considered as regulators of various cellular processes which may, for instance, control inflammatory processes, cancer formation and proliferation, but also bacterial, fungal and microbial growth. It is now apparent that redox control exerted by such natural and synthetic products may be used for prevention and therapy in Medicine and for the development of ‘green’ pesticides in Agriculture. This training network will study chemical, biochemical and biological aspects of the modulation of cellular redox balances by selected natural agents and their mimics. It relies on expertise of 10 full and 7 associated partners (1 SME) in a range of scientific disciplines, including synthetic, analytical, biological and pharmaceutical chemistry, biochemistry, cell biology, microbiology, cancer research and agricultural research. The network will address 4 36-month work packages (WP): A WP on natural antioxidants, inflammation and cancer; a WP studying intracellular redox control and signalling events triggered by external redox agents; a WP on green antibiotics and pesticides from plants and fungi; a WP on redox catalysts as agents selective against cancer and inflammatory cells. The network will provide interdisciplinary training for 4 experienced and 10 early stage researchers, all of which will acquire expertise in 3 or more of scientific disciplines. Each researcher will develop a training portfolio when joining the network. All early stage researchers are expected to obtain international recognised PhD degrees. In addition to intensive scientific training at various host institutes, there will be a framework programme offering training in science related matters and soft skills, such as logical and ethical aspects of research, IP, patenting and commercialisation, communication skills and cultural and gender issues.

Field of science

  • /natural sciences/biological sciences/cell biology
  • /natural sciences/biological sciences/microbiology/mycology
  • /natural sciences/biological sciences/microbiology/mycology/ethnomycology
  • /agricultural sciences/agriculture, forestry, and fisheries
  • /agricultural sciences/agriculture, forestry, and fisheries/agriculture
  • /natural sciences/biological sciences/biochemistry
  • /medical and health sciences/clinical medicine/oncology/cancer
  • /natural sciences/biological sciences/microbiology
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes

Call for proposal

FP7-PEOPLE-2007-1-1-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSITAT DES SAARLANDES
Address
Campus
66123 Saarbrucken
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 526 087,22
Administrative Contact
Vera Siegmund (Dr.)

Participants (9)

RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN
Germany
EU contribution
€ 192 359,20
Address
Templergraben 55
52062 Aachen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ernst Schmachtenberg (Prof.)
UNIVERSIDADE DE AVEIRO
Portugal
EU contribution
€ 194 993,70
Address
Campus Universitário De Santiago
3810-193 Aveiro
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Artur Silva (Prof.)
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 192 359,20
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations
Administrative Contact
Bettina Crispin (Ms.)
ECOSPRAY LIMITED
United Kingdom
EU contribution
€ 358 703,41
Address
Grange Farm, Cockley Cley Road
IP265BT Hilborough, Thetford, Norfolk
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
David Sadler-Bridge (Mr.)
THE UNIVERSITY OF EXETER
United Kingdom
EU contribution
€ 376 315,49
Address
The Queen's Drive Northcote House
EX4 4QJ Exeter
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Enda Clarke (Dr.)
RECHERCHES SCIENTIFIQUES LUXEMBOURG ASBL
Luxembourg
EU contribution
€ 206 800
Address
Hopital Kirchberg - Rue Edward Steichen 25
2540 Luxembourg
Activity type
Research Organisations
Administrative Contact
Marc Diederich (Dr.)
UNIVERSITE DE LORRAINE
France
EU contribution
€ 349 332,49
Address
Cours Leopold 34
54052 Nancy Cedex
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Julie Paysant (Ms.)
UNIVERSITE PARIS DESCARTES
France
EU contribution
€ 196 340,09
Address
Rue De L Ecole De Medecine 12
75270 Paris Cedex 06
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Patrick Berche (Prof.)
URSAPHARM Arzneimittel GmbH
Germany
EU contribution
€ 192 359,20
Address
Industriestr. 35
66129 Saarbruecken
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Peter Meiser (Dr.)