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SME-Academia Nuclear Receptor Knowledge Transfer

Objective

SME RECEPTOR is a transfer of knowledge programme which will bring top scientists from industry and academia together to address key questions in nuclear receptor research. The programme of research, which is implemented through the two way exchange of researchers between three leading research organisations and three specialist innovative SMEs, will develop methodology to tackle one of the most pressing medical challenges in Europe – characterization of the nuclear receptor role and the development of drugs targeting the complex symptoms characterized by the metabolic syndrome. SME RECEPTOR will exploit new opportunities for drug design provided by advances in bioinformatics and transgenic technology. This will enhance the understanding of basis mechanisms underlying nuclear receptor actions and their translation into the physiological regulation of diseases. Since cardiovascular toxicity is a major factor involved in both early and late drug failure, SME RECEPTOR will primarily focus on the development of early screening methods for cardiovascular toxicity, as well as to expand the knowledge of the governing molecular mechanisms. A key factor is the ability to translate the knowledge generated within this exchange programme into more advanced and efficient development of novel pharmaceuticals within the industry. The project will generate a group of scientists with unique knowledge and international expertise in nuclear receptor biology as well as nuclear receptor targeting pharmaceuticals. The mutually beneficial two way transfer of knowledge between industry and academia will provide a career boost to the researchers who will acquire leading new knowledge, complementary training and a detailed understanding of the research culture in their opposite sector. The project will further promote industry-academic networking, creating a strategic long-lasting industry-academia partnership.

Call for proposal

FP7-PEOPLE-2007-3-1-IAPP
See other projects for this call

Funding Scheme

MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)

Coordinator

KAROLINSKA INSTITUTET
Address
Nobels Vag 5
17177 Stockholm
Sweden
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 276 649
Administrative Contact
Ingemar Pongratz (Dr.)

Participants (5)

ECOLE NORMALE SUPERIEURE DE LYON
France
EU contribution
€ 182 939
Address
46 Allee D'italie
69364 Lyon
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Vincent Laudet (Prof.)
AliX S.A.
France
EU contribution
€ 373 308
Address
Rue Neuve 15
67540 Ostwald
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jean-Paul Renaud (Dr.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 161 265
Address
Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
Administrative Contact
Brice Kerber (Mr.)
WATCHFROG
France
EU contribution
€ 397 001
Address
4 Rue Pierre Fontaine
91000 Evry
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gregory Lemkine (Dr.)
Axcentua Pharmaceuticals AB
Sweden
EU contribution
€ 267 997
Address
Alfred Nobels Alle 10
14152 Huddinge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Stefan Rehnmark (Dr.)