Objective The overarching goal of COGS is to identify individuals with an increased risk of breast, ovary and prostate cancer. Furthermore, we will evaluate the effect of inherited genetic variation on tumour characteristics and clinical outcome. We will do this through quantifying the role of genetic and environmental/lifestyle risk in the largest data set ever generated. In all, we will include over 200,000 individuals in the COGS project. We will use detailed knowledge of the architecture of genetic susceptibility and interactions with environmental/lifestyle factors which will result in much more accurate individual risk prediction and improved intervention strategies. We are taking advantage of a unique possibility by incorporating seven existing consortia into one large project – COGS. Members of these consortia have collaborated successfully over the past years and results have been presented in world leading scientific journals such as Nature, Nature Genetics and Journal of the National Cancer Institute. These papers reflect that collaboration has been ongoing and that is has so far been very successful. We will also build on an existing European Commission project, TRANSBIG, thus adding value to already spent money. Results generated through COGS will lead to an improved understanding of the biological processes that underlie carcinogenesis, that in turn could guide new therapeutic strategies. Results will also lead to the development of new tests for risk prediction for breast, ovarian and prostate cancer. Fields of science medical and health sciencesclinical medicineoncologyprostate cancernatural sciencesbiological sciencesgenetics Keywords Breast cancer Gene-environment interaction Genetic susceptibility Ovarian cancer Prostate cancer lifestyle Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2007-2.4.1-11 - Epidemiology of gene-environment interactions involved in carcinogenesis Call for proposal FP7-HEALTH-2007-B See other projects for this call Funding Scheme CP-IP - Large-scale integrating project Coordinator KAROLINSKA INSTITUTET Address Nobels vag 5 17177 Stockholm Sweden See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Administrative Contact Agneta Haeggstroem (Ms.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 1 301 573,17 Participants (15) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom EU contribution € 3 796 030,40 Address Trinity lane the old schools CB2 1TN Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Administrative Contact Keith Cann (Mr.) Links Contact the organisation Opens in new window Website Opens in new window QUEENSLAND INSTITUTE OF MEDICAL RESEARCH Australia EU contribution € 0,00 Address Herston road, 300 QLD 4006 Herston See on map Activity type Research Organisations Administrative Contact Bronwyn Dunphy (Ms.) Links Contact the organisation Opens in new window Website Opens in new window DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG Germany EU contribution € 545 487,25 Address Im neuenheimer feld 280 69120 Heidelberg See on map Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Research Organisations Administrative Contact Bettina Crispin (Ms.) Links Contact the organisation Opens in new window Website Opens in new window FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III Spain EU contribution € 2 300 650,68 Address C melchor fernandez almagro 3 28029 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Research Organisations Administrative Contact Juan José Collazo Nieto (Mr.) Links Contact the organisation Opens in new window Website Opens in new window MAX IV Laboratory, Lund University Sweden EU contribution € 201 534,00 Address Paradisgatan 5c 22100 Lund See on map Region Södra Sverige Sydsverige Skåne län Activity type Higher or Secondary Education Establishments Administrative Contact Susanne André (Ms.) Links Contact the organisation Opens in new window Website Opens in new window HUS-YHTYMA Finland EU contribution € 201 471,60 Address Stenbackinkatu 9 00029 Helsinki See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Research Organisations Administrative Contact Mari Frostell (Ms.) Links Contact the organisation Opens in new window Website Opens in new window STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS Netherlands EU contribution € 1 087 739,60 Address Plesmanlaan 121 1066 CX Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Research Organisations Administrative Contact Henri Van Luenen (Dr.) Links Contact the organisation Opens in new window Website Opens in new window FOUNDATION FOR GENOMICS & POPULATION HEALTH United Kingdom EU contribution € 490 132,00 Address Worts causeway 2 CB1 8RN Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Research Organisations Administrative Contact Carol Lyon (Ms.) Links Contact the organisation Opens in new window KRAEFTENS BEKAEMPELSE Denmark EU contribution € 519 662,80 Address Strandboulevarden 49 2100 Koebenhavn See on map Region Danmark Hovedstaden Byen København Activity type Research Organisations Administrative Contact Claus Skytte Rasmussen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window BREAST INTERNATIONAL GROUP - AISBL Belgium EU contribution € 42 882,30 Address Boulevard de waterloo 121 1000 Bruxelles See on map Activity type Research Organisations Administrative Contact Livia Meirsman (Ms.) Links Contact the organisation Opens in new window Website Opens in new window INSTITUTE OF CANCER RESEARCH: THE ROYAL CANCER HOSPITAL LBG United Kingdom EU contribution € 600 674,80 Address Old brompton road 123 SW7 3RP London See on map Region London Inner London — West Kensington & Chelsea and Hammersmith & Fulham Activity type Higher or Secondary Education Establishments Administrative Contact Donna Conway (Ms.) Links Contact the organisation Opens in new window Website Opens in new window CENTRE DE LUTTE CONTRE LE CANCER LEON BERARD France EU contribution € 136 884,00 Address Rue laennec 28 69373 Lyon See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Research Organisations Administrative Contact Marina Rousseau-Tsangiris (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UCL Elizabeth Garrett Anderson Institute for Women’s Health United Kingdom EU contribution € 170 906,40 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Administrative Contact Greta Borg-Carbott (Ms.) Links Contact the organisation Opens in new window Website Opens in new window CANCER COUNCIL VICTORIA Australia EU contribution € 0,00 Address 615 st kilda road 3004 Melbourne victoria See on map Activity type Research Organisations Administrative Contact Priscilla Hinds (Ms.) Links Contact the organisation Opens in new window Website Opens in new window THE UNIVERSITY OF WARWICK United Kingdom EU contribution € 319 872,00 Address Kirby corner road - university house CV4 8UW Coventry See on map Region West Midlands (England) West Midlands Coventry Activity type Higher or Secondary Education Establishments Administrative Contact Peter Hedges (Dr.) Links Contact the organisation Opens in new window Website Opens in new window
