Objectif
Calcium phosphate ceramics have been used in medicine for more than 20 years because of its similarities to bone apatite. Bone repair and regeneration occurs along its surface and porous structures permits bone ingrowths acting as a scaffold in bony tissues sites. As well as these ceramics, bioactive glasses and biocompatible polymers are widely used but all of them present low strength and poor fatigue resistance to be implanted as high load bearing devices. In order to seek better ways of processing biomaterials, so that both mechanical properties and porosity could be optimized, devices have been design combining HA with other materials, however, significant amounts of the reinforcing phases are needed to achieve the desired properties, and as these parts are significantly less bioactive than HA, or bioreabsorble, the ability of the composite to form a stable interface is poor compared to HA itself. An ideal reinforcement material would impart mechanical integrity without diminishing its properties. This project envisages the use of carbon nanotubes (CNTs) as reinforcement material for the bioactive ceramics and to use their ability as drug delivery systems of pharmacological active molecules (osteogenic, antitumoral, antiviric,…) or as smart materials (able to change their properties as a function of the medium). In relation to this, the addition of CNTs to the base composite produces a three-dimensional electrical conducting network, property as has already been reported, could be used to provide electrical stimulation and increase of cellular proliferation.
Champ scientifique (EuroSciVoc)
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN. Voir: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN. Voir: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- sciences naturellessciences chimiqueschimie inorganiquemétal alcalinoterreux
- sciences naturellessciences chimiquesscience des polymères
- ingénierie et technologiebiotechnologie industriellebiomatériaux
- ingénierie et technologieingénierie des materiauxcéramique
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Appel à propositions
FP7-PEOPLE-2007-2-2-ERG
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Régime de financement
MC-ERG - European Re-integration Grants (ERG)Coordinateur
28040 Madrid
Espagne