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Contained Molecular Farming – Controllable Contained Systems for High Yield and Consistency


Advances in shaking technologies

Autores: Jochen Büchs; Wolf Klöckner
Publicado en: Elsevier BV 2012
Identificador permanente: Digital Object Identifier:10.1016/j.tibtech.2012.03.001

Animal component-free Agrobacterium tumefaciens cultivation media for better GMP-compliance increases biomass yield and pharmaceutical protein expression in Nicotiana benthamiana.

Autores: Kathrin Wenzel; Stefan Schillberg; Stefan Schillberg; Marcel Houdelet; Tanja Holland; Johannes F. Buyel; Johannes F. Buyel; Anna Galinski
Publicado en: Wiley Biotechnology journal : BTJ 12(4), 1600721 (2017). doi:10.1002/biot.201600721 2017
Identificador permanente: Digital Object Identifier:10.1002/biot.201600721; PubMed ID:28221723; Digital Object Identifier:10.18154/rwth-2017-04874

Correlation between mass transfer coefficient kLa and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale

Autores: Tibor Anderlei; Clemens Lattermann; Stefan Schillberg; Wolf Klöckner; Jochen Büchs; Nicole Raven; Riad Gacem
Publicado en: BioMed Central Journal of biological engineering 7(28), 14 S. (2013). doi:10.1186/1754-1611-7-28 2013
Identificador permanente: Digital Object Identifier:10.1186/1754-1611-7-28; PubMed Central ID:PMC4177207; PubMed ID:24289110; Digital Object Identifier:10.18154/rwth-conv-082919

Molecular Farming in Tobacco Hairy Roots

Autores: Kirsi-Marja Oksman-Caldentey; Stefan Schillberg; Juha-Pekka Pitkänen; Marja-Leena Laukkanen; Tibor Anderlei; Suvi T. Häkkinen; Dirk Bosch; Maurice Henquet; Anneli Ritala; Nicole Raven; Richard M. Twyman
Identificador permanente: urn:urn:nbn:nl:ui:32-445847; Digital Object Identifier:10.1002/bit.25113

Power input correlation to characterize the hydrodynamics of cylindrical orbitally shaken bioreactors

Autores: Stéphanie Tissot; Wolf Klöckner; Jochen Büchs; Florian M. Wurm
Identificador permanente: Digital Object Identifier:10.1016/j.bej.2012.04.007

Optimization of BY‐2 cell suspension culture medium for the production of a human antibody using a combination of fractional factorial designs and the response surface method

Autores: Nicole Raven; Stefan Schillberg; Stefan Schillberg; Nikolay Vasilev; Rainer Fischer; Rainer Fischer; Ulrike Grömping; Anja Lipperts
Identificador permanente: Digital Object Identifier:10.1111/pbi.12079

Regulatory approval and a first‐in‐human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants

Autores: Julia Boyle; Friedrich Altmann; Philip J. Dale; Valerie Isitt; Markus Sack; Richard M. Twyman; Tom Cole; Penelope Hundleby; Martin Lobedan; Craig J. van Dolleweerd; Thomas William Rademacher; Gabriela Stiegler; Paul Christou; Julian K.-C. Ma; Jürgen Drossard; Brigitta Vcelar; Rainer Fischer; Mathew J. Paul; Dietmar Katinger; David J. M. Lewis; Hubert Mertens; Eva Stoger
Identificador permanente: Digital Object Identifier:10.1111/pbi.12416; Handle:10459.1/58877

Critical Analysis of the Commercial Potential of Plants for the Production of Recombinant Proteins.

Autores: Nicole Raven; Stefan Rasche; Stefan Rasche; Holger Spiegel; Stefan Schillberg; Stefan Schillberg; Matthias Buntru
Publicado en: Frontiers Media SA Frontiers in Plant Science, Vol 10 (2019) 2019
Identificador permanente: Digital Object Identifier:10.3389/fpls.2019.00720; PubMed Central ID:PMC6579924; PubMed ID:31244868