Objective
Enantioselective catalysis is the most important frontier of synthetic organic chemistry today. As nature uses enzymes to catalyze highly stereoselective reactions, it was long assumed that large and complex structures are essential to attain high enantioselectivity. However, it has now been illustrated by MacMillan and others that small molecule organic catalysts can compete with the enantioselectivity and reactivity levels of enzymes, omitting the need for highly toxic organometallic catalysts or “strong” Lewis acids. The availability of enantiopure organic chemicals as well as the academic, industrial, environmental and economic benefits of organocatalysis has shown the importance of this field of research. The combination of more than one chemical transformation into a cascade sequence is also an expanding area of research due to the reduction in cost, energy and waste. The proposed outgoing phase project would further the development of a new enantioselective organocatalytic method, within the pioneering research group of Prof. David MacMillan at Princeton. The MacMillan group have consistently been at the forefront of organocatalysis research, and thus far have pioneered over 30 catalytic asymmetric transformations of immense practicality and synthetic utility. The return phase project would highlight the importance of domino reaction sequences in organic synthesis today, with the implementation of a 3-step cascade in the total synthesis of an anti-cancer molecule. The mobility, importance of the research topic and high profile collaboration between 2 world-class research institutes would increase scientific excellence and provide opportunity to widely advertise participation in Marie Curie actions. Overall, a highly motivated European scientist would benefit greatly from both phases whilst developing many new skills. Important networks of international communication would be established, providing a platform for further collaborations in the future.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry
- natural sciences chemical sciences catalysis
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IOF-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
YO10 5DD YORK NORTH YORKSHIRE
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.