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New tools and approaches to control Porcine Reproductive and Respiratory Syndrome (PRRS) in the EU and Asia

Objective

Porcine reproductive and respiratory syndrome virus (PRRSV) is the major cause of reproductive and respiratory problems in pigs worldwide. Controlling this disease is a top priority in pig producing countries. Due to mutations at a high frequency, new variants of the virus appear that are no longer effectively controlled by the commercial vaccines. In addition, highly virulent variants emerge, leading to high losses. With regard to animal welfare and agricultural economics, there is an urgent need to control PRRS. Furthermore, the abusive use of antibiotics to control PRRSV-associated respiratory problems may lead to resistance that may endanger public health. PoRRSCon is an initiative of 14 partners originating from Europe and Asia with strong expertises in virology and immunology. They are doing frontline research on PRRSV and/or vaccine development. Two of these partners are leading European pharmaceutical companies that will guide the consortium in the direction of exploitable results. By joining their strengths they have an ideal position to be successful in one of the most difficult challenges in pig health, controlling PRRS. To reach this final goal, the following objectives are forwarded:(i) characterize genetically and antigenically current PRRSV isolates in Europe and Asia, (ii) have a better understanding of the complex pathogenesis of PRRSV infections, immune response against PRRSV and immune modulation by PRRSV, (iii) define the genetic base of PRRSV virulence, (iv) identify PRRSV proteins and domains on these viral proteins that are involved in the induction of the immunity against PRRSV and in the immune modulation of PRRSV, (v) develop new generation, efficacious and safe marker vaccines that can be adapted to temporary changes and geographical differences and (vi) develop DIVA assays that allow to differentiate infected from vaccinated animals. At the end, it will be possible to set up a control strategy by combining marker vaccines with DIVA assays

Field of science

  • /medical and health sciences/health sciences/infectious disease/RNA virus/coronavirus

Call for proposal

FP7-KBBE-2009-3
See other projects for this call

Funding Scheme

CP-FP-SICA - Small/medium-scale focused research project for specific cooperation actions dedicated to international cooperation partner countries(SICA)

Coordinator

UNIVERSITEIT GENT
Address
Sint Pietersnieuwstraat 25
9000 Gent
Belgium
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 461 100
Administrative Contact
Saskia Vanden Broeck (Ms.)

Participants (15)

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 259 700
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
Carlos Manuel Abad Ruiz (Mr.)
FUNDACIO CENTRE DE RECERCA EN SANITAT ANIMAL CRESA
Spain
EU contribution
€ 199 728
Address
Universidad Autonoma De Barcelona Edifici Cresa
08193 Barcelona
Activity type
Research Organisations
Administrative Contact
Silvia Pratsavall (Ms.)
INMUNOLOGIA Y GENETICA APLICADA SA
Spain
EU contribution
€ 200 070
Address
C/ Hermanos Garcia Noblejas 41-2
28037 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Rodriguez Maria Jose (Ms.)
PARCO TECNOLOGICO PADANO S.R.L.
Italy
EU contribution
€ 159 980
Address
Via Einstein - Localita Cascina Codazza
26900 Lodi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gianluca Carenzo (Dr.)
EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG

Participation ended

Switzerland
Address
Bundeshaus Ost
3003 Bern
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Caroline De St. Simon (Ms.)
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 259 600
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lars Erik Lars (Dr.)
PANSTWOWY INSTYTUT WETERYNARYJNY - PANSTWOWY INSTYTUT BADAWCZY
Poland
EU contribution
€ 199 999
Address
Partyzantow 57
24100 Pulawy
Activity type
Research Organisations
Administrative Contact
Tomasz Stadejek (Dr.)
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 159 905
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Angela Noble (Ms.)
Food and Environment Research Agency
United Kingdom
EU contribution
€ 259 859
Address
Area 1A, Nobel House, Smith Square 17
SW1P 3JR London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lucinda Cranham (Ms.)
STICHTING WAGENINGEN RESEARCH
Netherlands
EU contribution
€ 259 990
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Research Organisations
Administrative Contact
Annemarie Rebel (Dr.)
Shanghai Veterinary Research Institute - Chinese Academy of Agricultural Sciences
China
EU contribution
€ 128 200
Address
Ziyue Road 518
200241 Shanghai
Activity type
Research Organisations
Administrative Contact
Shishan Yuan (Dr.)
MINISTRY OF AGRICULTURE AND RURAL DEVELOPMENT
Vietnam
EU contribution
€ 97 725
Address
Lane 78, Giai Phong 15
844 Hanoi
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Van Long Nguyen (Dr.)
BOEHRINGER INGELHEIM VETMEDICA GMBH
Germany
EU contribution
€ 13 200
Address
Binger Strasse 173
55218 Ingelheim
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Vicky Fachinger (Dr.)
CHINA AGRICULTURAL UNIVERSITY
China
EU contribution
€ 80 000
Address
Yuanmingyuan Xilu 2 Haidian District
100193 Beijing
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ruying Gao (Ms.)
EIDGENOESSISCHES DEPARTEMENT DES INNERN
Switzerland
EU contribution
€ 260 014
Address
Inselgasse 1
3003 Bern
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Caroline De St. Simon