Objective The consortium will discover and carry to the stage of development candidates, plant derived small molecules with potential as new cosmetic and agrochemical agents. These compounds will derive from plants originating from major biodiversity hotspots in Europe, Africa, Latin America, and the Asia-Pacific region. The starting point of the project will be a diversity-oriented natural product library of 500 compounds from the existing compound repositories of three project partners. Screening of this compound library in assay panels for agrochemical (antifungal, herbicidal, insecticidal) and cosmetic properties (UV-protection, anti-aging, anti-hyperpigmentation) will rapidly identify promising scaffolds. This knowledge will serve as entry points for a chemotaxonomy and chemodiversity oriented collection of plants which are thought to contain structural variants and decorations of these scaffolds. A liquid library of 3600 extracts will be generated and screened. Stringent prioritization and profiling procedures will generate 100 compounds as focused sub-libraries around the privileged scaffolds. A state-of-the-art technology platform for miniaturized natural product discovery will be used for the purpose. Evaluation of these sub-libraries will lead to 30 compounds which will undergo advanced testing to qualify 5 compounds as development candidates for novel agrochemical and/or cosmetic agents with new or improved properties over existing active ingredients. An additional outcome of the project will be an extract library with a unprecedented level of associated spectroscopic information and metadata, to be used for future purposes. The high-caliber consortium brings together international leaders in small molecule natural products, bioprospection, leading industries in agrochemistry, cosmetics, and spectroscopic data management and analysis. Fields of science natural sciencesbiological sciencesecologyecosystems Programme(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Topic(s) KBBE-2009-3-1-04 - Prospecting for novel plant-produced compounds Call for proposal FP7-KBBE-2009-3 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON EU contribution € 706 753,40 Address 6 CHRISTOU LADA STR 10561 Athina Greece See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Administrative Contact Efi Kafentzi (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITAT BASEL Switzerland EU contribution € 378 045,00 Address PETERSPLATZ 1 4051 Basel See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Matthias Hamburger (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 665 301,60 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Véronique Debisschop (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSIDAD DE PANAMA Panama EU contribution € 80 680,00 Address CALLE MANUEL ESPINOSA BATISTA SN 0824 Panama See on map Activity type Higher or Secondary Education Establishments Administrative Contact Betty Ann Rowe De Catsambanis (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH South Africa EU contribution € 210 243,00 Address Meiring Naude Road, Brummeria 46 0001 Pretoria See on map Activity type Research Organisations Administrative Contact Sandy Farnworth (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data BASF SE Germany EU contribution € 308 690,00 Address CARL BOSCH STRASSE 38 67063 Ludwigshafen Am Rhein See on map Region Rheinland-Pfalz Rheinhessen-Pfalz Ludwigshafen am Rhein, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Michael Roeper (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KORRES S.A. NATURAL PRODUCTS (KORRES ANONIMI ETERIA FYSIKA PROIONTA) Greece EU contribution € 281 120,00 Address 57th Km ATHENS-LAMIA NATIONAL ROAD 32011 INOFYTA See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Dimitris Vidakis (Mr.) Links Contact the organisation Opens in new window Total cost No data BRUKER BIOSPIN GMBH Germany EU contribution € 172 800,00 Address RUDOLF-PLANK-STRASSE 23 76275 Ettlingen See on map Region Baden-Württemberg Karlsruhe Karlsruhe, Landkreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Eberhard Eckert (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" Greece EU contribution € 100 000,00 Address END OF PATRIARCHOU GRIGORIOU E AND 27 NEAPOLEOS STREET 15341 Agia Paraskevi See on map Region Αττική Aττική Βόρειος Τομέας Αθηνών Activity type Research Organisations Administrative Contact Marina Fontara Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
