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The Commercialisation of Transglutaminase.

Objetivo

The TRANSCOM project is designed to facilitate the exchange of knowledge and technology between 3 leading European research teams and 4 SMEs each with an interest in the protein crosslinking enzymes Transglutaminases. Transglutaminases are a widely distributed group of enzymes that catalyse the post-translational modification of proteins by the formation of isopeptide bonds or by deamidation of proteins. The deregulation of enzyme activity generally associated with major disruptions in cellular/tissue homeostasis can result in a number of human diseases TRANSCOM will be involved in the invention, development and production of diagnostic kits and treatments for health problems related to the activity of transglutaminases. The project will establish the molecular nature of the role of transglutaminases in the pathogenesis of diseases such as coeliac disease, neurodegeneration and intravenous catheter infections which are known to involve their cross-linking activity. The proposed work programme will develop new knowledge to address gaps in our understanding of this field and transfer existing knowledge and skills between sectors. It will build and broaden the capability of the partners with the objective of accelerating the development of new strategies that can be used in diagnosis and treatment of coeliac disease, neurodegeneration and in the prevention of infections like MRSA associated with intravenous catheters.

Convocatoria de propuestas

FP7-PEOPLE-2009-IAPP
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Coordinador

ASTON UNIVERSITY
Dirección
Aston Triangle
B4 7ET Birmingham
United Kingdom

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Martin Griffin (Prof.)
Aportación de la UE
€ 582 165

Participantes (6)

TAMPEREEN YLIOPISTO
Finlandia
Aportación de la UE
€ 284 064
Dirección
Kalevantie 4
33014 Tampere

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Markku Mäki (Prof.)
DEBRECENI EGYETEM
Hungría
Aportación de la UE
€ 144 286
Dirección
Egyetem Ter 1
4032 Debrecen

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
László Fésüs (Prof.)
Ani Biotech Oy
Finlandia
Aportación de la UE
€ 170 239
Dirección
Museokatu 13b
00100 Helsinki

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Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Mika Saramäki (Mr.)
UD-GENOMED MEDICAL GENOMIC TECHNOLOGIES KUTATAS-FEJLESZTESI ES SZOLGALTATO KFT
Hungría
Aportación de la UE
€ 94 772
Dirección
Nagyerdei Krt 98
4032 Debrecen

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Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Gabor Zahuczky (Dr.)
COVALAB SAS
Francia
Aportación de la UE
€ 193 781
Dirección
Avenue Albert Einstein 11
69100 Villeurbanne

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Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Said El Alaoui (Dr.)
X-Link Limited

La participación finalizó

United Kingdom
Aportación de la UE
€ 210 941
Dirección
Biocity Nottingham, Pennyfoot Street
NG1 1GF Nottingham

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Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Richard Neil Barnes (Dr.)