Objectif Conventional orthopedic implants and dental filling approaches are only partly successful in preventing load-bearing failures and long-term durability, respectively. The problem in the current materials for bone repair and regeneration is that none of them has the hierarchical structure of natural bone that incorporates inorganic crystals with organic molecules. Any long-lasting biomimetic bone-like material should be designed from a well-dispersed inorganic nanoparticle phase in an organic matrix. This work is going to accomplish the following objectives: 1) Development of organic/apatite hybrid biomaterials based on apatite nanoparticles dispersed in a polymer gel. 2) Determination of physicochemical factors affecting the self-assembly of the hybrid material. 3) Characterization of micro- and nano-structure of the hybrid material. 4) Evaluation of mechanical strength and interfacial characteristics of the self-assembled biomaterial. Micro-/nano-structural characterization of this new biohybrid material will be done by using several techniques to investigate material composition and morphology. The mechanical properties of the designed biomaterial will be tested. The outcomes of this research will provide a novel approach for bone regeneration and will serve as a basis for future in-vivo experiments with the long-term goal of repairing bone defects. Champ scientifique natural scienceschemical sciencespolymer sciencesengineering and technologynanotechnologynano-materialsengineering and technologyindustrial biotechnologybiomaterialsmedical and health sciencesmedical biotechnologyimplantsartificial bone Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) FP7-PEOPLE-2009-RG - Marie Curie Action: "Reintegration Grants" Appel à propositions FP7-PEOPLE-2009-RG Voir d’autres projets de cet appel Régime de financement MC-IRG - International Re-integration Grants (IRG) Coordinateur BOGAZICI UNIVERSITESI Contribution de l’UE € 100 000,00 Adresse BEBEK 34342 Istanbul Turquie Voir sur la carte Région İstanbul İstanbul İstanbul Type d’activité Higher or Secondary Education Establishments Contact administratif Gulay Barbarosoglu (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
