Objective The emergence of suicidality in patients receiving drug treatment is of concern because of the overall burden and the possible link with completed suicide. The lack of uniform requirements for defining, detecting and recording suicidality and the presence of disease related confounders create major problems. It is possible that Medication-Related Suicidality (MRS) differs from Psychopathology-Related Suicidality (PRS) in terms of phenomenology, clinical expression and time course, and may vary between children and adults. Unlike PRS, the time-course of MRS may be associated with possible differences in drug pharmacokinetics; abrupt onset; absence of suicidality prior to start of medication; and emergence of suicidality related co-morbidities after treatment.This proposal will focus on developing a web-based comprehensive methodology for the assessment and monitoring of suicidality and its mediators in children and adolescents using the HealthTrackerTM (a paediatric web-based health outcome monitoring system), with the aim of developing a Suicidality Assessment and Monitoring Module, a Bio-psycho-social Mediators of Suicidality Assessment Module, and a Suicidality-Related Psychiatric and Physical Illness Module. The information obtained will be used to computer-generate classification of suicidality using the Classification of Suicide-Related Thoughts and Behaviour (Silverman et al, 2007) and the Columbia Classification Algorithm of Suicidal Assessment (C-CASA) (Posner et al, 2007). The existing Medication Characteristics Module will be expanded to allow documentation of pharmacological characteristics of medication, to explore whether they mediate MRS. The methodology will then be tested in 3 paediatric observational trials (risperidone in conduct disorder; fluoxetine in depression, and montelukast in bronchial asthma) and standardized, which can be used pharmacovigilance and in epidemiological, observational, and registration trials. Fields of science medical and health sciencesclinical medicinepneumologyasthmamedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsmedical and health sciencesbasic medicinepharmacology and pharmacypharmacokineticsmedical and health sciencesclinical medicinepaediatrics Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2010.4.2-3 - Adverse Drug Reaction Research. FP7-HEALTH-2010-single-stage Call for proposal FP7-HEALTH-2010-single-stage See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator KING'S COLLEGE LONDON Address Strand WC2R 2LS London United Kingdom See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Paul Labbett (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 1 119 023,19 Participants (18) Sort alphabetically Sort by EU Contribution Expand all Collapse all STICHTING RADBOUD UNIVERSITEIT Netherlands EU contribution € 37 058,02 Address Houtlaan 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Administrative Contact Maarten Van Langen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window ACADEMISCH ZIEKENHUIS GRONINGEN Netherlands EU contribution € 27 972,82 Address Hanzeplein 1 9713 GZ Groningen See on map Region Noord-Nederland Groningen Overig Groningen Activity type Higher or Secondary Education Establishments Administrative Contact J.J. Breeuwsma (Mr.) Links Contact the organisation Opens in new window Website Opens in new window ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT Germany EU contribution € 71 775,90 Address Square j 5 68159 Mannheim See on map Region Baden-Württemberg Karlsruhe Mannheim, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Ralf Dittmann (Prof.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAET ULM Germany EU contribution € 100 294,16 Address Helmholtzstrasse 16 89081 Ulm See on map Region Baden-Württemberg Tübingen Ulm, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Frank Gleixner (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY OF DUNDEE United Kingdom EU contribution € 60 231,22 Address Nethergate DD1 4HN Dundee See on map Region Scotland Eastern Scotland Angus and Dundee City Activity type Higher or Secondary Education Establishments Administrative Contact Peter Peek (Mr.) Links Contact the organisation Opens in new window Website Opens in new window THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON Participation ended United Kingdom EU contribution € 85 000,00 Address Brunswick square 29-39 WC1N 1AX London See on map Activity type Higher or Secondary Education Establishments Administrative Contact Macey Murrey (Dr.) Links Contact the organisation Opens in new window Website Opens in new window ASSISTANCE PUBLIQUE HOPITAUX DE PARIS France EU contribution € 109 900,05 Address 55 boulevard diderot 75012 Paris See on map Region Ile-de-France Ile-de-France Val-de-Marne Activity type Research Organisations Administrative Contact Christophe Misse (Mr.) Links Contact the organisation Opens in new window Website Opens in new window CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P. Spain EU contribution € 85 896,49 Address Calle monforte de lemos 5 28029 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Research Organisations Administrative Contact Manuel Sanchez Delgado (Mr.) Links Contact the organisation Opens in new window Website Opens in new window FUNDACIO DE RECERCA CLINIC BARCELONA-INSTITUT D INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER Spain EU contribution € 184 891,12 Address Carrer rossello 149 08036 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Administrative Contact Sara Jane Hurst (Ms.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA DEGLI STUDI DI CAGLIARI Italy EU contribution € 165 745,53 Address Via universita 40 09124 Cagliari See on map Region Isole Sardegna Cagliari Activity type Higher or Secondary Education Establishments Administrative Contact Giuseppina Tore (Ms.) Links Contact the organisation Opens in new window True Clarity Limited Participation ended United Kingdom EU contribution € 143 610,00 Address Londonderry farm, keynsham road, the hay barn BS30 6EL Willsbridge See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Andrew Davies (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UCL Elizabeth Garrett Anderson Institute for Women’s Health United Kingdom EU contribution € 113 941,00 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Administrative Contact Greta Borg-Carbott (Ms.) Links Contact the organisation Opens in new window Website Opens in new window INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 41 006,00 Address Rue de tolbiac 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Annick Bertault (Ms.) Links Contact the organisation Opens in new window Website Opens in new window CONCENTRIS RESEARCH MANAGEMENT GMBH Germany EU contribution € 300 467,54 Address Ludwigstr. 4 82256 Furstenfeldbruck See on map Region Bayern Oberbayern Fürstenfeldbruck Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Ameli Schwalber (Ms.) Links Contact the organisation Opens in new window Website Opens in new window GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUST Participation ended United Kingdom EU contribution € 0,00 Address Great ormond street WC1N 3JH London See on map Region London Inner London — West Camden and City of London Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Claire Newton (Ms.) Links Contact the organisation Opens in new window THE GOVERNORS OF THE UNIVERSITY OF ALBERTA Canada EU contribution € 0,00 Address 1-560 enterprise square 10230 jasper avenue research services office T5J 4P6 Edmonton alberta See on map Activity type Higher or Secondary Education Establishments Administrative Contact Julaine Herst (Ms.) Links Contact the organisation Opens in new window HEALTHTRACKER LTD United Kingdom EU contribution € 305 420,00 Address Foxon close 18 CR3 5SY Caterham See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Nikola Penkov (Mr.) Links Contact the organisation Opens in new window Website Opens in new window CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER France EU contribution € 47 766,96 Address Avenue du doyen gaston giraud 191 34000 Montpellier See on map Region Occitanie Languedoc-Roussillon Hérault Activity type Research Organisations Administrative Contact Valerie Handweiler (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window
