Understanding food-gut-brain mechanisms across the lifespan in the regulation of hunger and satiety for health

Project Information

FULL4HEALTH

Grant agreement ID: 266408

Project closed

Start date 1 February 2011

End date 31 January 2016

Funded under

• Specific Programme "Cooperation": Food, Agriculture and Biotechnology

Total cost € 11 793 561,60

EU contribution € 8 992 613,00

Coordinated by

THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
United Kingdom

Objective

Full4Health is a multidisciplinary European collaboration of internationally renowned laboratories investigating the mechanisms of hunger, satiety and feeding behaviour, effects of dietary components and food structure on these processes, and their possible exploitation in addressing obesity, chronic disease and under-nutrition. The proposal integrates investigation of both human volunteers (dietary/exercise intervention studies and administration of encapsulated nutrients) and laboratory animals with emphasis on neuronal, hormonal, molecular, physiological and psychological responses to food at different stages of the life course. We will apply imaging and other cutting edge technologies in both humans and rodents to answer critical research questions at different levels of the food-gut-brain axis. In human volunteers, responses to diet will be investigated from childhood through to the elderly, whereas wide-ranging cutting-edge rodent studies will investigate related issues such as early developmental programming the food-gut-brain axis, multiple feedback signalling interactions, and inflammation-induced anorexia. The project will examine the interaction of food and dietary components with the gastrointestinal tract, and will characterise the role of gut endocrine secretions, the vagus nerve, and hindbrain, hypothalamic and forebrain structures in signalling and integration of hunger and satiety. Physiological and psychological responses to food may change as we develop and age, with impact on food choices and preferences. This is a critical issue in the battle against food intake-related chronic disease, most commonly driven by over-consumption, but also in consideration of relative under-nutrition in the elderly and clinically compromised.

Fields of science

• medical and health sciences › health sciences › nutrition › obesity

Programme(s)

• FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology

Topic(s)

• KBBE.2010.2.2-01 - Neurological pathways regulating hunger/satiety and gut behaviour - Call: FP7-KBBE-2010-4

Call for proposal

FP7-KBBE-2010-4
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

• EU contribution: € 1 759 172,00
• Address: KING'S COLLEGE REGENT WALK ; AB24 3FX ABERDEEN ; United Kingdom
• Region: Scotland › North Eastern Scotland › Aberdeen City and Aberdeenshire
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Elizabeth Rattray (Dr.)
• Total cost: No data

Participants (14)

CHAROKOPEIO PANEPISTIMIO

Greece

• EU contribution: € 577 263,00
• Address: ELEFTHERIOU VENIZELOU 70 ; 176 71 ATHINA
• Region: Αττική › Aττική › Νότιος Τομέας Αθηνών
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Souliotis Jim (Mr.)
• Total cost: No data

UNIVERSITY OF LEEDS

United Kingdom

• EU contribution: € 401 896,00
• Address: WOODHOUSE LANE ; LS2 9JT Leeds
• Region: Yorkshire and the Humber › West Yorkshire › Leeds
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Kathy Brownridge (Ms.)
• Total cost: No data

UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Netherlands

• EU contribution: € 1 091 388,00
• Address: HEIDELBERGLAAN 100 ; 3584 CX Utrecht
• Region: West-Nederland › Utrecht › Utrecht
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Roger Adan (Prof.)
• Total cost: No data

UNIVERSITEIT MAASTRICHT

Netherlands

• EU contribution: € 790 000,00
• Address: MINDERBROEDERSBERG 4 ; 6200 MD Maastricht
• Region: Zuid-Nederland › Limburg (NL) › Zuid-Limburg
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: M.S. Westerterp-Plantenga (Prof.)
• Total cost: No data

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

United Kingdom

• EU contribution: € 1 048 053,00
• Address: TRINITY LANE THE OLD SCHOOLS ; CB2 1TN Cambridge
• Region: East of England › East Anglia › Cambridgeshire CC
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Gaynor Hollander (Ms.)
• Total cost: No data

GOETEBORGS UNIVERSITET

Sweden

• EU contribution: € 680 000,00
• Address: VASAPARKEN ; 405 30 Goeteborg
• Region: Södra Sverige › Västsverige › Västra Götalands län
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Emilia Rung (Dr.)
• Total cost: No data

NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU

Norway

• EU contribution: € 349 801,00
• Address: HOGSKOLERINGEN 1 ; 7491 Trondheim
• Region: Norge › Trøndelag › Trøndelag
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Duan Chen (Dr.)
• Total cost: No data

THE UNIVERSITY OF EDINBURGH

United Kingdom

• EU contribution: € 437 421,00
• Address: OLD COLLEGE, SOUTH BRIDGE ; EH8 9YL Edinburgh
• Region: Scotland › Eastern Scotland › Edinburgh
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Angela Noble (Ms.)
• Total cost: No data

Université Lille 2 Droit et Santé

France

• EU contribution: € 354 000,00
• Address: Rue Paul Duez ; 59000 LILLE
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Marie Gompel (Dr.)
• Total cost: No data

MW ENCAP LIMITED

United Kingdom

• EU contribution: € 143 458,00
• Address: STATION ROAD OLD STATION WORKS 1 ; SG86P2 Royston
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Paul Higgins (Mr.)
• Total cost: No data

KLINIKUM DER UNIVERSITAET ZU KOELN

Germany

• EU contribution: € 356 400,00
• Address: Kerpener Strasse 62 ; 50937 Koeln
• Region: Nordrhein-Westfalen › Köln › Köln, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Jens C. Bruening (Prof.)
• Total cost: No data

KOBENHAVNS UNIVERSITET

Denmark

• EU contribution: € 355 080,00
• Address: NORREGADE 10 ; 1165 Kobenhavn
• Region: Danmark › Hovedstaden › Byen København
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Ivan Kristoffersen (Mr.)
• Total cost: No data

DANONE GLOBAL RESEARCH & INNOVATION CENTER BV

Netherlands

• EU contribution: € 71 750,00
• Address: UPPSALALAAN 12 ; 3584 CT Utrecht
• Region: West-Nederland › Utrecht › Utrecht
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Klaske Van Norren (Dr.)
• Total cost: No data

WAGENINGEN UNIVERSITY

Netherlands

• EU contribution: € 576 931,00
• Address: DROEVENDAALSESTEEG 4 ; 6708 PB Wageningen
• Region: Oost-Nederland › Gelderland › Veluwe
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Tom Bessems (Mr.)
• Total cost: No data