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Content archived on 2024-06-18

Systematic Analysis of Gene Synergies to Discover Drug Synergies

Objective

Using multitherapeutics against disease is a promising direction in medicine. A particularly useful drug combination is a synergistic drug pair, where two drugs administered together produce a collective effect better than the added independent effects of both. Since drug interaction screening is an expensive experiment, most synergistic drug pairs are found by serendipity. In this proposal, we describe a research plan which aims to develop predictive tools for drug synergy. During the proposed research, drug pairs with synergistic antifungal activity will be discovered. A preliminary study has shown that these predictive tools are likely to succeed. The results of the proposed research will lead to a better understanding of drug interactions and their potential in medicine.

Call for proposal

FP7-PEOPLE-2010-RG
See other projects for this call

Coordinator

SABANCI UNIVERSITESI
EU contribution
€ 75 000,00
Address
ORTA MAHALLE UNIVERSITE CADDESI N 27 TUZLA
34956 Istanbul
Türkiye

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Region
İstanbul İstanbul İstanbul
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Zeynep Birsel
Links
Total cost
No data