Objective
"Every third protein contains metal as cofactor. Cu-enzymes plays crucial rules in key processes in bioenergetics, mitochondrial respiration, neurotransmitter biosynthesis, antioxidation and pigmentation Therefore they are intensive targets for discovering new drugs and the understanding of their structure-functions relationships will provide new insight in translational and biomedical research.
In this Marie Curie International Outgoing Fellowship I will investigate the mechanism of important two bi nuclear cupper enzyme – Peptidylglycine α-Amidating Monooxygenase (PAM) and Dopamine β-Monooxygense (DBM) which catalyze hydroxylation of substrates in crucial importance for neurobiology . The miss functionalities of these enzymes are related with nervous system disorders therefore revealing it mechanism will provide advanced opportunities for design of new drugs. In order to achieve this knowledge we will apply integrated combination of the most advanced spectroscopic techniques and state of the art computational methods."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- natural sciences computer and information sciences computational science
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IOF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NE1 8ST NEWCASTLE UPON TYNE
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.