Objective Falls are a major public health concern that directly affects millions of elderly Europeans, the healthcare system, and the adult children and caregivers of older people. The V-TIME approach combines cutting edge technology with emerging concepts from gerontology, neuroscience and rehabilitation to reduce fall risk in a unique way. The V-TIME multi-modal intervention consists of treadmill training (TT) that promotes walking abilities and physical fitness. A key novel addition is the simultaneous use of a virtual reality (VR) environment that challenges, implicitly teaches and enhances cognitive skills that facilitate the safe execution of many activities of daily living: visual scanning, planning, dual tasking abilities, and obstacle negotiation.Exciting pilot studies support the idea that TT augmented with VR (TT+VR) addresses the limitations of existing fall prevention interventions. Via TT+VR, V-TIME offers task-specific training in a motivating and safe environment that can readily be reproduced and standardized. The major goal of the current proposal is to establish the beneficial effects of V-TIME training in a large (n=300) and diverse group of elderly via a multi-centre, prospective randomized controlled trial. Outcomes include post-training 6 month fall incidence rates (the primary outcome), gait, physical activity (e.g. steps walked in 7 days), cognitive function, quality of life, and neuroimaging measures (fNIRS, fMRI). The effects of dosing and an extension phase will be examined (n=60). The consortium brings together world leaders in ageing, neuroscience, rehabilitation and VR technology to test a new therapy that may dramatically reduce the negative costs of falls, financial and other. The RCT is designed to show that V-TIME offers a significant and clinically relevant greater benefit compared to current clinical management; to probe brain plasticity; and to establish efficacy on fall risk, mobility, cognitive function, and functional independence. Fields of science medical and health scienceshealth sciencespublic healthmedical and health sciencesclinical medicinegerontologynatural sciencescomputer and information sciencessoftwaresoftware applicationsvirtual reality Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2011.2.2.2-1 - Investigator-driven clinical trials for therapeutic interventions in elderly populations Call for proposal FP7-HEALTH-2011-two-stage See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator THE FOUNDATION FOR MEDICAL RESEARCH INFRASTRUCTURAL DEVELOPMENT AND HEALTH SERVICES NEXT TO THE MEDICAL CENTER TEL AVIV Address Weizmann street 6 64239 Tel aviv Israel See on map Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 1 043 090,00 Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all KATHOLIEKE UNIVERSITEIT LEUVEN Belgium EU contribution € 680 190,00 Address Oude markt 13 3000 Leuven See on map Region Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY OF NEWCASTLE UPON TYNE United Kingdom EU contribution € 673 469,60 Address Kings gate NE1 7RU Newcastle upon tyne See on map Region North East (England) Northumberland and Tyne and Wear Tyneside Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA DEGLI STUDI DI GENOVA Italy EU contribution € 685 547,00 Address Via balbi 5 16126 Genova See on map Region Nord-Ovest Liguria Genova Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window STICHTING RADBOUD UNIVERSITEIT Netherlands EU contribution € 963 652,00 Address Houtlaan 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA DEGLI STUDI DI SASSARI Italy EU contribution € 271 800,00 Address Piazza universita 21 07100 Sassari See on map Region Isole Sardegna Sassari Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window INITION LIMITED United Kingdom EU contribution € 461 300,00 Address Curtain road 23 EC2A 3LT London See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window BEACON TECH LTD Israel EU contribution € 402 500,00 Address Golda meir st 3 74036 Ness ziona See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window ADVANCED DRUG DEVELOPMENT SERVICES - ADDS SRO Czechia EU contribution € 600 408,20 Address Jana uhra 168/10 602 00 Brno See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window