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Dengue research Framework for Resisting Epidemics in Europe

Objetivo

"WHO estimates that one of the main consequences of global warming will be an increased burden of vector-borne diseases. Among these, dengue appears to be particularly problematic, with tens of millions of cases of dengue fever estimated to occur annually, including up to 500,000 cases of the life-threatening dengue hemorrhagic fever/dengue shock syndrome. In recent years, the global burden of dengue disease has been rising dramatically and this prolific increase has been connected to societal changes such as population growth, urbanization and the transport of infected hosts and vectors. In addition, rising temperatures and global climate change may lead to the expansion of the range of major mosquito vectors, extension of the transmission season in areas with currently circulating dengue virus and increase in the mosquito spp. vectorial capacity. Active surveillance to detect in-coming dengue virus (DENV) in regions at the limits of DENV circulation are an important initial step in the prevention of dengue epidemics in Europe. Asymptomatic infections likely play a crucial role in the initial invasion process and DENV transmission and, although hitherto ignored, must be addressed.
Using retrospective and prospective data from Asia, the main objectives of the program are (1) to identify key factors determining dengue transmission, outcome of infection and epidemics; (2) the development of novel diagnostic tools to detect asymptomatic infections. We will estimate the risk of DENV spreading to uninfected areas, especially in Southern Europe where susceptible vector exists. The major tools generated will be predictive models that enable specific interventions to reduce epidemic probability and diagnostic methods for surveillance. Inherent in this approach is the belief that improved surveillance and diagnosis of the asymptomatic dengue carriers will contribute to effective intervention, especially during early stages of pathogen invasion into a naïve region."

Convocatoria de propuestas

FP7-HEALTH-2011-single-stage
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Coordinador

INSTITUT PASTEUR
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Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
Francia
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Research Organisations
Aportación de la UE
€ 1 396 860,04
Contacto administrativo
Sophie Ablott (Mrs.)

Participantes (14)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
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€ 429 791,80
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South Kensington Campus Exhibition Road
SW7 2AZ London
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Higher or Secondary Education Establishments
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Scott Wheatley (Mr.)
BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN
Alemania
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€ 336 560
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Bernhard Nocht Strasse 74
20359 Hamburg
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Research Organisations
Contacto administrativo
Michael Schreiber (Dr.)
MAHIDOL UNIVERSITY
Tailandia
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€ 574 280
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Ratchawithi Road 420/6
10400 Bangkok
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Higher or Secondary Education Establishments
Contacto administrativo
Pornpimon Adams (Ms.)
INSTITUT PASTEUR DU CAMBODGE FOUNDATION
Camboya
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€ 821 504,20
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Boulevard Monivong 5
000 Phnom Penh
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Research Organisations
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Paul Horwood (Dr.)
FUNDACIO INSTITUT CATALA DE CIENCIES DEL CLIMA
España
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€ 399 304,50
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Carrer Doctor Trueta 203 3R Pis
08005 Barcelona
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Research Organisations
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Carine Saüt (Ms.)
UNIVERSITE DE ROUEN NORMANDIE
Francia
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€ 356 800
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Rue Thomas Becket 1 Mont Saint Aignan
76821 Mont Saint Aignan Cedex
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Higher or Secondary Education Establishments
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Philippe Moguérou (Dr.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Francia
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€ 236 168
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Rue Michel Ange 3
75794 Paris
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Other
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Julie Zittel (Ms.)
FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP
Portugal
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€ 288 000
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Campo Grande Edificio C1 Piso 3
1749 016 Lisboa
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Research Organisations
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Livia Moreira (Ms.)
IPATIMUP - INSTITUTO DE PATOLOGIA E IMUNOLOGIA MOLECULAR DA UNIVERSIDADE DO PORTO PCUP
Portugal
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€ 267 600
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Rua Julio Amaral De Carvalho 45
4200 135 Porto
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Ana Sofia Santos Silva (Dr.)
BIOCOMPUTING PLATFORMS LTD OY
Finlandia
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€ 213 960
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Innopoli 3 Vaisalantie 6
02130 Espoo
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Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Timo Kanninen (Mr.)
AMPTEC GMBH
Alemania
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€ 324 480
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Koenigstrasse 4A
22767 Hamburg
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Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Guido Krupp (Dr.)
RIOTECH PHARMACEUTICALS LTD
United Kingdom
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€ 204 480
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Albert Street 6
CB4 3BE Cambridge
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Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Mark Thursz (Prof.)
INSTITUTO DE MEDICINA TROPICAL PEDRO KOURI
Cuba
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€ 109 273,46
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Autopista Novia Mediodia Km 6 1/2
11300 La Habana
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Maria Guadalupe Guzman (Prof.)
INSTITUT LOUIS MALARDE
Polinesia Francesa
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€ 40 000
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Rue Du 5 Mars 1797
98713 Papeete
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Research Organisations
Contacto administrativo
Van-Mai Cao-Lormeau (Dr.)