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Dengue research Framework for Resisting Epidemics in Europe

Obiettivo

"WHO estimates that one of the main consequences of global warming will be an increased burden of vector-borne diseases. Among these, dengue appears to be particularly problematic, with tens of millions of cases of dengue fever estimated to occur annually, including up to 500,000 cases of the life-threatening dengue hemorrhagic fever/dengue shock syndrome. In recent years, the global burden of dengue disease has been rising dramatically and this prolific increase has been connected to societal changes such as population growth, urbanization and the transport of infected hosts and vectors. In addition, rising temperatures and global climate change may lead to the expansion of the range of major mosquito vectors, extension of the transmission season in areas with currently circulating dengue virus and increase in the mosquito spp. vectorial capacity. Active surveillance to detect in-coming dengue virus (DENV) in regions at the limits of DENV circulation are an important initial step in the prevention of dengue epidemics in Europe. Asymptomatic infections likely play a crucial role in the initial invasion process and DENV transmission and, although hitherto ignored, must be addressed.
Using retrospective and prospective data from Asia, the main objectives of the program are (1) to identify key factors determining dengue transmission, outcome of infection and epidemics; (2) the development of novel diagnostic tools to detect asymptomatic infections. We will estimate the risk of DENV spreading to uninfected areas, especially in Southern Europe where susceptible vector exists. The major tools generated will be predictive models that enable specific interventions to reduce epidemic probability and diagnostic methods for surveillance. Inherent in this approach is the belief that improved surveillance and diagnosis of the asymptomatic dengue carriers will contribute to effective intervention, especially during early stages of pathogen invasion into a naïve region."

Campo scientifico

  • /scienze naturali/scienze biologiche/microbiologia/virologia
  • /scienze mediche e della salute/scienze della salute/malattie infettive/virus a RNA

Invito a presentare proposte

FP7-HEALTH-2011-single-stage
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Meccanismo di finanziamento

CP-FP-SICA - Small/medium-scale focused research project for specific cooperation actions dedicated to international cooperation partner countries(SICA)
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinatore

INSTITUT PASTEUR
Indirizzo
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
Francia
Tipo di attività
Research Organisations
Contributo UE
€ 1 396 860,04
Contatto amministrativo
Sophie Ablott (Mrs.)

Partecipanti (14)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
Contributo UE
€ 429 791,80
Indirizzo
South Kensington Campus Exhibition Road
SW7 2AZ London
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Scott Wheatley (Mr.)
BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN
Germania
Contributo UE
€ 336 560
Indirizzo
Bernhard Nocht Strasse 74
20359 Hamburg
Tipo di attività
Research Organisations
Contatto amministrativo
Michael Schreiber (Dr.)
MAHIDOL UNIVERSITY
Thailandia
Contributo UE
€ 574 280
Indirizzo
Ratchawithi Road 420/6
10400 Bangkok
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Pornpimon Adams (Ms.)
INSTITUT PASTEUR DU CAMBODGE FOUNDATION
Cambogia
Contributo UE
€ 821 504,20
Indirizzo
Boulevard Monivong 5
000 Phnom Penh
Tipo di attività
Research Organisations
Contatto amministrativo
Paul Horwood (Dr.)
FUNDACIO INSTITUT CATALA DE CIENCIES DEL CLIMA
Spagna
Contributo UE
€ 399 304,50
Indirizzo
Carrer Doctor Trueta 203 3R Pis
08005 Barcelona
Tipo di attività
Research Organisations
Contatto amministrativo
Carine Saüt (Ms.)
UNIVERSITE DE ROUEN NORMANDIE
Francia
Contributo UE
€ 356 800
Indirizzo
Rue Thomas Becket 1 Mont Saint Aignan
76821 Mont Saint Aignan Cedex
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Philippe Moguérou (Dr.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Francia
Contributo UE
€ 236 168
Indirizzo
Rue Michel Ange 3
75794 Paris
Tipo di attività
Research Organisations
Contatto amministrativo
Julie Zittel (Ms.)
FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP
Portogallo
Contributo UE
€ 288 000
Indirizzo
Campo Grande Edificio C1 Piso 3
1749 016 Lisboa
Tipo di attività
Research Organisations
Contatto amministrativo
Livia Moreira (Ms.)
IPATIMUP - INSTITUTO DE PATOLOGIA E IMUNOLOGIA MOLECULAR DA UNIVERSIDADE DO PORTO PCUP
Portogallo
Contributo UE
€ 267 600
Indirizzo
Rua Julio Amaral De Carvalho 45
4200 135 Porto
Tipo di attività
Research Organisations
Contatto amministrativo
Ana Sofia Santos Silva (Dr.)
BIOCOMPUTING PLATFORMS LTD OY
Finlandia
Contributo UE
€ 213 960
Indirizzo
Innopoli 3 Vaisalantie 6
02130 Espoo
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Timo Kanninen (Mr.)
AMPTEC GMBH
Germania
Contributo UE
€ 324 480
Indirizzo
Koenigstrasse 4A
22767 Hamburg
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Guido Krupp (Dr.)
RIOTECH PHARMACEUTICALS LTD
United Kingdom
Contributo UE
€ 204 480
Indirizzo
Albert Street 6
CB4 3BE Cambridge
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Mark Thursz (Prof.)
INSTITUTO DE MEDICINA TROPICAL PEDRO KOURI
Cuba
Contributo UE
€ 109 273,46
Indirizzo
Autopista Novia Mediodia Km 6 1/2
11300 La Habana
Tipo di attività
Research Organisations
Contatto amministrativo
Maria Guadalupe Guzman (Prof.)
INSTITUT LOUIS MALARDE
Polinesia francese
Contributo UE
€ 40 000
Indirizzo
Rue Du 5 Mars 1797
98713 Papeete
Tipo di attività
Research Organisations
Contatto amministrativo
Van-Mai Cao-Lormeau (Dr.)