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Innovative gene therapies for epilepsy treatment

Objective

A significant part of the costs of neurological diseases on society is associated with epilepsy. About 30-40% of the patients are refractory to pharmacological treatments, which are mostly symptomatic and often have side effects. In few cases surgical intervention is considered and no treatments interfering with or preventing the development of epilepsy are currently available. In this context, EPIXCHANGE aims at exploring, providing the basis for clinical application and implementing in the industrial arena new and unconventional strategies for the therapy of partial epilepsy advancing the state-of-the-art in the field. To achieve this, a strategic partnership will be created, including two internationally recognized academic institutions (UniFE, ULund) and one SME (NsGene) developing encapsulated cell biodelivery (ECB) based therapeutic products. ECBs will be transferred to the academic partners, while knowledge and technology on animal models, viral vectors and BDNF-producing cells will be transferred to the SME.
This partnership will implement a joint research programme, which will enable to exploit the complementary competencies and technologies available at each participant site and will increase the knowledge-sharing and technology transfer, as well as the mutual understanding and penetration of the different cultural settings and skills required for both academic and industrial sectors, thus improving partners’ RTD capability and competitiveness.
This will be combined with transfer of knowledge on complementary skills. Experienced researchers will be also recruited to bring top level experience in techniques that are not present in the consortium. Annual workshops will be organized to benefit the transfer of knowledge programme and the dissemination of results both within the consortium and towards the scientific community.

Call for proposal

FP7-PEOPLE-2011-IAPP
See other projects for this call

Coordinator

UNIVERSITA DEGLI STUDI DI FERRARA
Address
Via Ariosto 35
44121 Ferrara
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 460 536
Administrative Contact
Dario Di Luca (Prof.)

Participants (3)

MAX IV Laboratory, Lund University
Sweden
EU contribution
€ 371 544
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mérab Kokaia (Dr.)
NSGENE AS
Denmark
EU contribution
€ 485 283
Address
Baltorpvej 154
2750 Ballerup
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jette Lindskov (Ms.)
BIOVIRON SARL
France
EU contribution
€ 109 413
Address
Rue Marcelin Berthelot 5
69680 Chassieu
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Hervé Berthommé (Dr.)