Skip to main content

Psychiatric Diagnostic and Prevention Consortium

Objective

PsychDPC contains leading European centres in genetics and psychiatry, richly endowed with expertise in both clinical and basic research. The partners bring together state-of-the-art technical facilities, high academic standards as well as established training activities, which will be utilized in concert to maximise the outcome of the project. The primary aim of PsychDPC is to translate data emerging from large-scale research efforts in genetic and genomic epidemiology of schizophrenia, conducted on large sets of well-characterized volunteer patients, into information of relevance to current practice and future clinical advances. PsychDPC will do this through effective integration of data between the partners. A range of complementary approaches will be applied with an initial focus on: 1) Discovery of novel genetic susceptibility variants from genome wide SNP association data through expanding the large sample sets accessible to partners and by imputing available sequence data into the large genotyped datasets, 2) study of the phenotypic stamp conferred by copy number variations (CNVs) and genes harbouring non-synonymous point mutations conferring high and moderate risk of schizophrenia, 3) powerful novel genetic approaches to genetic discovery including long range phasing combined with deep sequencing and 4) analysis of the relationship of uncovered variants conferring risk of schizophrenia with clinical, neurpsychological and brain structure phenotypes. The consortium has unique, very large samples from schizophrenia patients and the aim is to re-phenotype subjects carrying variants conferring high-risk to identify their specific cognitive and behavioural features. Combined with a refinement of familial risk assessment, using comprehensive national registry databases, we will utilise our findings to develop diagnostic tools, tools for early intervention and genetic counselling.

Field of science

  • /natural sciences/biological sciences/genetics and heredity/genome
  • /medical and health sciences/clinical medicine/psychiatry/schizophrenia

Call for proposal

FP7-PEOPLE-2011-IAPP
See other projects for this call

Funding Scheme

MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)

Coordinator

ISLENSK ERFDAGREINING EHF
Address
Sturlugotu 8
101 Reykjavik
Iceland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 899 817
Administrative Contact
Frosti Jonsson (Mr.)

Participants (5)

KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 157 491
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Labbett (Mr.)
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Participation ended

Germany
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dan Rujescu (Prof.)
REGION HOVEDSTADEN
Denmark
EU contribution
€ 292 129
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Thomas Werge (Dr.)
UNIVERSITETET I OSLO
Norway
EU contribution
€ 235 370
Address
Problemveien 5-7
0313 Oslo
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Randi Stene (Ms.)
MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG
Germany
EU contribution
€ 194 452
Address
Universitaetsplatz 10
6108 Halle (Saale)
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sigrid Köhne (Dr.)