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Application of new technologies and methods in nutrition research – the example of phenotypic flexibility

Objective

NutriTech will build on the foundations of traditional human nutrition research using cutting-edge analytical technologies and methods to comprehensively evaluate the diet-health relationship and critically assess their usefulness for the future of nutrition research and human well-being. Technologies include genomics, transcriptomics, proteomics, metabolomics, laser scanning cytometry, NMR based lipoprotein profiling and advanced imaging by MRI/MRS.

All methods will be applied in an integrated manner to quantify the effect of diet on “phenotypic flexibility”, based on metabolic flexibility (the capacity for the organism to adapt fuel oxidation to fuel availability). However, NutriTech will move beyond the state-of-the-art by applying these integrated methods to assess the underlying and related cell biological and genetic mechanisms and multiple physiological processes of adaptation when homeostasis is challenged. Methods will in the first instance be evaluated within a human intervention study, and the resulting optimal methods will be validated in a number of existing cohorts against established endpoints.

NutriTech will disseminate the harmonised and integrated technologies on a global scale by a large academic network including 6 non-EU partners and by providing an integrated and standardised data storage and evaluation platform. The impact of NutriTech will be multifold and exploitation is crucial as major breakthroughs from our technology and research are expected. This will be achieved by collaboration with a consortium of 8 major food industries and by exploitation of specific technologies by our 6 SME partners. Overall, NutriTech will lay the foundations for successful integration of emerging technologies intro nutrition research.

Field of science

  • /medical and health sciences/basic medicine/physiology/homeostasis
  • /natural sciences/chemical sciences/electrochemistry/electrolysis
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/proteomics
  • /natural sciences/physical sciences/optics/laser physics
  • /medical and health sciences/health sciences/nutrition

Call for proposal

FP7-KBBE-2011-5
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Address
Anna Van Buerenplein 1
2595 DA Den Haag
Netherlands
Activity type
Research Organisations
EU contribution
€ 802 014
Administrative Contact
Ben Van Ommen (Dr.)

Participants (23)

TECHNISCHE UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 545 000
Address
Arcisstrasse 21
80333 Muenchen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Katrin Hörmann (Ms.)
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 1 247 645
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tatjana Palalic (Ms.)
UNIVERSITETET I OSLO
Norway
EU contribution
€ 376 150
Address
Problemveien 5-7
0313 Oslo
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eva Helene Mjelde (Ms.)
WAGENINGEN UNIVERSITY
Netherlands
EU contribution
€ 581 361
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tom Bessems (Mr.)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 373 060
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Donal Doolan (Mr.)
Medical University Of Varna
Bulgaria
EU contribution
€ 252 800
Address
55 Marin Drinov Str.
9002 Varna
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Diana Ivanova (Prof.)
CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER
France
EU contribution
€ 366 386
Address
150 Cours Albert Thomas
69372 Lyon Cedex 08
Activity type
Other
Administrative Contact
Augustin Scalbert (Dr.)
ISTITUTO SUPERIORE DI SANITA

Participation ended

Italy
Address
Viale Regina Elena 299
00161 Roma
Activity type
Research Organisations
Administrative Contact
Rosa Maria Martoccia (Dr.)
UNIVERSIDAD DE CORDOBA
Spain
EU contribution
€ 120 000
Address
Avenida De Medina Azahara 5
14005 Cordoba
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Carmen Tarradas Iglesias (Prof.)
Vereniging European Nutrigenomics Organisation
Netherlands
EU contribution
€ 71 784
Address
Bomenweg 2
6703 HD Wageningen
Activity type
Research Organisations
Administrative Contact
Freerk Pepping (Dr.)
INTERNATIONAL LIFE SCIENCES INSTITUTE EUROPEAN BRANCH AISBL
Belgium
EU contribution
€ 300 000
Address
Av. E. Mounier 83
1200 Bruxelles
Activity type
Research Organisations
Administrative Contact
Nico Van Belzen (Dr.)
EDI Experimentelle Diagnostische Immunologie GmbH
Germany
EU contribution
€ 43 200
Address
Aspenhaustrasse
72770 Reutlingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Joos (Dr.)
PAPRIKA-BIOANALTYTICS SZOLGALTATO ESTANACSADO BT
Hungary
EU contribution
€ 225 000
Address
Balassa Balint Utca 10
4032 Debrecen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Enikö Lazar (Mr.)
VITAS AS
Norway
EU contribution
€ 297 000
Address
Gaustadalleen 21
0349 Oslo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Gundersen (Dr.)
BIQUALYS BV
Netherlands
EU contribution
€ 121 200
Address
Dreijenlaan 3
6703 HA Wageningen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jacques Vervoort (Dr.)
BIOCRATES LIFE SCIENCES AG
Austria
EU contribution
€ 83 860
Address
Eduard Bodem Gasse 8 1 Stock
6020 Innsbruck
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Denise Sonntag (Dr.)
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA UNIVERSITY OF ALBERTA
Canada
Address
Street 8625 112 Campus Tower 222 Research Services Office
T6G 2E1 Edmonton Alberta
Activity type
Higher or Secondary Education Establishments
Administrative Contact
David Wishart (Dr.)
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Canada
Address
Kings College Circle 27
M5S 1A1 Toronto
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Krista Montgomery (Ms.)
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
Australia
Address
Clunies Ross Street Csiro Black Mountain Science And Innovation Park
2601 Acton Act
Activity type
Research Organisations
Administrative Contact
Michael Fenech (Prof.)
THE UNIVERSITY OF AUCKLAND
New Zealand
Address
Princes Street 24
1010 Auckland
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kate Harrower (Ms.)
FUNDACION IMDEA ALIMENTACION
Spain
EU contribution
€ 105 000
Address
Pabellon Central Del Antiguo Hospital De Cantoblan Edificio Numero 7- Carretera Madrid- Colmenar Viejo--kilometro 14
28049 Madrid
Activity type
Research Organisations
Administrative Contact
Inmaculada Galindo (Ms.)
TRUSTEES OF TUFTS COLLEGE NON PROFIT CORPORATION
United States
Address
Professors Row 20 169
02155 Medford Ma
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Joyce Ferland
CEINGE BIOTECNOLOGIE AVANZATE SCARL
Italy
EU contribution
€ 75 030
Address
Via Gaetano Salvatore 486
80145 Napoli
Activity type
Research Organisations
Administrative Contact
Floriana Di Giacomo