Skip to main content
European Commission logo print header

Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production

Objective

The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial strains, artificial industrial microbial strains will be designed. This will enable the access to genetically robust and safe strains with added/novel functionalities and topologies from renewable resources. These strains will be characterized with alternative reading of the genetic code (genetic firewall) and with predetermined chemistries (metathesis), as well as necessary robustness for efficient industrial use.

Call for proposal

FP7-KBBE-2011-5
See other projects for this call

Coordinator

TECHNISCHE UNIVERSITAT BERLIN
Address
Strasse des 17 juni 135
10623 Berlin
Germany

See on map

Region
Berlin Berlin Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Silke Hönert (Ms.)
Links
EU contribution
No data

Participants (7)