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Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production

Ziel

The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial strains, artificial industrial microbial strains will be designed. This will enable the access to genetically robust and safe strains with added/novel functionalities and topologies from renewable resources. These strains will be characterized with alternative reading of the genetic code (genetic firewall) and with predetermined chemistries (metathesis), as well as necessary robustness for efficient industrial use.

Aufforderung zur Vorschlagseinreichung

FP7-KBBE-2011-5
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Koordinator

TECHNISCHE UNIVERSITAT BERLIN
Adresse
Strasse Des 17 Juni 135
10623 Berlin
Deutschland
Aktivitätstyp
Higher or Secondary Education Establishments
EU-Beitrag
€ 898 809
Kontakt Verwaltung
Silke Hönert (Ms.)

Beteiligte (7)

Isthmus
Frankreich
EU-Beitrag
€ 343 992
Adresse
Rue Saint Amand 31
75015 Paris
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Pierre Dedenys (Mr.)
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Schweiz
EU-Beitrag
€ 499 237
Adresse
Raemistrasse 101
8092 Zuerich
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Sven Panke (Prof.)
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgien
EU-Beitrag
€ 250 000
Adresse
Oude Markt 13
3000 Leuven
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Sarah Malevé (Ms.)
UNIVERSITAT BASEL
Schweiz
EU-Beitrag
€ 249 600
Adresse
Petersplatz 1
4051 Basel
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Thomas Ward (Prof.)
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Frankreich
EU-Beitrag
€ 249 780
Adresse
Rue Leblanc 25
75015 Paris 15
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Mathilde Suret (Ms.)
MOLECULAR NETWORKS GMBH COMPUTERCHEMIE
Deutschland
EU-Beitrag
€ 241 200
Adresse
Neumeyerstr 28-34
90411 Nurnberg
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Johann Gasteiger (Prof.)
BIOFACTION KG
Österreich
EU-Beitrag
€ 264 320
Adresse
Kundmanngasse 39/12
1030 Wien
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Markus Schmidt (Dr.)