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A systematic analysis of parasite metabolism - from metabolism to intervention

Objective

Parasites exact a devastating toll on health and economic productivity, infecting man and also domestic livestock. Drugs used to combat parasitic diseases are deficient in many ways and new, better drugs are needed to establish sustainable means to combat diseases caused by protozoan parasites that include malaria, trypanosomiasis and leishmaniasis in man, and coccidiosis among others in animals. This ITN will train a new generation of European scientists in the requisites of preclinical drug discovery, combining academic excellence in innovation with industrial rigor and thus providing training from an industrial and academic perspective. The programme works on the premise that parasite metabolism offers a multitude of potential targets that can be exploited for drug design. Advances in genomics, transcriptomics, metabolomics and protein chemistry, alongside computational systems biology are integral to the activities of the network. The programme is populated with projects at all levels of the preclinical drug discovery cascade to ensure ESRs and ERs are exposed to requirements and aspects of every step of this process. Therefore aspects of drug design, medicinal chemistry and small molecule screening will also be central to the programme. ESRs will perform research in two different laboratories providing them with multidisciplinary intersectoral training that we consider essential for the development of a highly skilled, knowledgeable new generation of researchers capable of innovation and application of research in a research area of global importance to human health..

Call for proposal

FP7-PEOPLE-2011-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSITY OF GLASGOW
Address
University Avenue
G12 8QQ Glasgow
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 203 431
Administrative Contact
Michael Barrett (Prof.)

Participants (11)

UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES

Participation ended

France
Address
Place Eugene Bataillon 2
34095 Montpellier
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jean-Michel Portefaix (Mr.)
STICHTING RADBOUD UNIVERSITEIT
Netherlands
EU contribution
€ 243 834
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Geurt Van Renselaar (Mr.)
UNIVERSITY OF LEEDS
United Kingdom
EU contribution
€ 261 201
Address
Woodhouse Lane
LS2 9JT Leeds
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Martin Hamilton (Mr.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 254 096
Address
Rue Michel Ange 3
75794 Paris
Activity type
Other
Administrative Contact
Florence Parnier (Ms.)
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
EU contribution
€ 226 626
Address
Seminarstrasse 2
69117 Heidelberg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christine Clayton (Prof.)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
EU contribution
€ 508 192
Address
147 Rue De L'universite
75007 Paris Cedex 07
Activity type
Research Organisations
Administrative Contact
Nicolas Combebiac (Mr.)
UNIVERSITE DE MONTPELLIER
France
EU contribution
€ 254 096
Address
163 Rue Auguste Broussonnet
34090 Montpellier
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jean-Michel Portefaix (Mr.)
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 228 205
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
Alberto Sereno Alvarez (Mr.)
FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA
Spain
EU contribution
€ 228 205
Address
Avda Del Conocimiento 3
18100 Armilla Granada
Activity type
Research Organisations
Administrative Contact
Olga Genilloud (Dr.)
INTERVET INTERNATIONAL BV
Netherlands
EU contribution
€ 211 851
Address
Wim De Korverstraat 35
5831 AN Boxmeer
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Paul M. Selzer (Prof.)
GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO SL
Spain
EU contribution
€ 196 966
Address
C/ Severo Ochoa Numero 2 Parque Tecnologico De Mad
28760 Tres Cantos Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Julio Martin (Dr.)